N-(2-naphthalen-1-yl-4-oxofuro[3,2-c]chromen-3-yl)benzamide | 1447565-64-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: N-(2-naphthalen-1-yl-4-oxofuro[3,2-c]chromen-3-yl)benzamide
• CAS: 1447565-64-1
• 化学式: C₂₈H₁₇NO₄
• 分子量: 431.447
• InChiKey: MBOYOPNDAPWJSJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  33
• 可旋转键数：
  3
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  68.5
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-萘乙酮 在 selenium(IV) oxide 作用下， 以 溶剂黄146 为溶剂， 反应 0.5h， 生成 N-(2-naphthalen-1-yl-4-oxofuro[3,2-c]chromen-3-yl)benzamide
  参考文献：
  名称：

  Regiospecific Synthesis of Novel Furo[4,5-c]coumarins in a One-Pot Reaction

  摘要：

  A new and expedient assembly of an interesting class of amido-substituted furo[4,5-c]coumarins has been successfully achieved through a one-pot sequential coupling and cyclization strategy starting from 4-hydroxycoumarin, aryl glyoxals and benzamide. All the reactions showed selectivity towards furo[4,5-c]coumarin, instead of the corresponding isoxazolo-substituted coumarins.

  DOI：

  10.1055/s-0032-1316895

文献信息

• Regiospecific Synthesis of Novel Furo[4,5-c]coumarins in a One-Pot Reaction
  作者：Bahador Karami、Saeed Khodabakhshi、Khalil Eskandari

  DOI：10.1055/s-0032-1316895

  日期：——

  A new and expedient assembly of an interesting class of amido-substituted furo[4,5-c]coumarins has been successfully achieved through a one-pot sequential coupling and cyclization strategy starting from 4-hydroxycoumarin, aryl glyoxals and benzamide. All the reactions showed selectivity towards furo[4,5-c]coumarin, instead of the corresponding isoxazolo-substituted coumarins.