| 1528564-19-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• CAS: 1528564-19-3
• 化学式: C₁₂H₁₉N₃O₅
• 分子量: 285.3
• InChiKey: VLQJHSQYLXRXPA-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  反应 48.0h， 以100%的产率得到
  参考文献：
  名称：

  Synthesis and conformational behavior of pseudopeptides containing δ-azaproline. A cis conformational preference for Xaa1–δ-azaPro bond

  摘要：

  delta-Azaproline, a new bis-nitrogen proline surrogate has been used in order to control the conformation of an AA-Psi Pro bond. Conformational analysis of Xaa(1)-delta-azaPro-Xaa(3) performed by NMR, IR experiments, and molecular modeling revealed a preference for a trans conformation of the Xaa(1)-delta-azaPro bond when delta-azaPro is protected by a Boc group. The removal of the Boc protection leads to the establishment of a C-10 pseudocycle via a hydrogen bond network favoring the cis conformation of the Xaa(1)-delta-azaPro bond. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.11.049