5-(4-pyridin-3-ylphenyl)-2,3'-bipyridine | 1253279-50-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 5-(4-pyridin-3-ylphenyl)-2,3'-bipyridine
• 英文别名: 2-Pyridin-3-yl-5-(4-pyridin-3-ylphenyl)pyridine；2-pyridin-3-yl-5-(4-pyridin-3-ylphenyl)pyridine
• CAS: 1253279-50-3
• 化学式: C₂₁H₁₅N₃
• 分子量: 309.37
• InChiKey: HHJONGKPICGMBJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-bromo-5-(4-bromophenyl)pyridine 、 3-吡啶硼酸 在 四(三苯基膦)钯 、 sodium carbonate 作用下， 以 1,4-二氧六环 、 水 为溶剂， 以41%的产率得到5-(4-pyridin-3-ylphenyl)-2,3'-bipyridine
  参考文献：
  名称：

  Synthesis of new phenylpyridyl scaffolds using the Garlanding approach

  摘要：

  One-pot reaction for the synthesis of novel phenylpyridyl derivatives and mixed quater phenylpyridyl compounds is described by using the Garlanding approach The reactions proceed with moderate to good yields in mild conditions and good reaction times This work represents a second application of the simplicity and versatility of Garlanding concept for the construction of new phenylpyridyl scaffolds. which can be considered as non-peptidic foldamer alpha-helix numerics. (C) 2010 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tet.2010.08.008

文献信息

• Synthesis of new phenylpyridyl scaffolds using the Garlanding approach
  作者：Anne Sophie Voisin-Chiret、Marilena Muraglia、Grégory Burzicki、Serge Perato、Filomena Corbo、Jana Sopková-de Oliveira Santos、Carlo Franchini、Sylvain Rault

  DOI：10.1016/j.tet.2010.08.008

  日期：2010.10

  One-pot reaction for the synthesis of novel phenylpyridyl derivatives and mixed quater phenylpyridyl compounds is described by using the Garlanding approach The reactions proceed with moderate to good yields in mild conditions and good reaction times This work represents a second application of the simplicity and versatility of Garlanding concept for the construction of new phenylpyridyl scaffolds. which can be considered as non-peptidic foldamer alpha-helix numerics. (C) 2010 Published by Elsevier Ltd.