(3-Cyano-2-oxochromen-7-yl) 4-oxopentanoate | 1334740-01-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• 英文名称: (3-Cyano-2-oxochromen-7-yl) 4-oxopentanoate
• 英文别名: (3-cyano-2-oxochromen-7-yl) 4-oxopentanoate
• CAS: 1334740-01-0
• 化学式: C₁₅H₁₁NO₅
• 分子量: 285.256
• InChiKey: DHFFLFCTMHHKCF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  93.5
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (3-Cyano-2-oxochromen-7-yl) 4-oxopentanoate 在 肼 作用下， 以 二甲基亚砜 为溶剂， 生成 3-氰基-7-羟基香豆素
  参考文献：
  名称：

  Hydrazine-Selective Chromogenic and Fluorogenic Probe Based on Levulinated Coumarin

  摘要：

  Chemosignaling of hydrazine by selective deprotection of levulinated coumarin was investigated. In the presence of hydrazine, levulinated coumarin was selectively deprotected, resulting in chromogenic and fluorescent turn-on type signaling. The selective naked-eye detectable signaling of hydrazine was possible in the presence of representative metal ions and common anions in an aqueous environment.

  DOI：

  10.1021/ol202136q
• 作为产物：
  描述：

  3-氰基-7-羟基香豆素 、 4-羰基戊酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以65%的产率得到(3-Cyano-2-oxochromen-7-yl) 4-oxopentanoate
  参考文献：
  名称：

  Hydrazine-Selective Chromogenic and Fluorogenic Probe Based on Levulinated Coumarin

  摘要：

  Chemosignaling of hydrazine by selective deprotection of levulinated coumarin was investigated. In the presence of hydrazine, levulinated coumarin was selectively deprotected, resulting in chromogenic and fluorescent turn-on type signaling. The selective naked-eye detectable signaling of hydrazine was possible in the presence of representative metal ions and common anions in an aqueous environment.

  DOI：

  10.1021/ol202136q

文献信息

• Hydrazine-Selective Chromogenic and Fluorogenic Probe Based on Levulinated Coumarin
  作者：Myung Gil Choi、Jiyoung Hwang、Jung Ok Moon、Jaeyoung Sung、Suk-Kyu Chang

  DOI：10.1021/ol202136q

  日期：2011.10.7

  Chemosignaling of hydrazine by selective deprotection of levulinated coumarin was investigated. In the presence of hydrazine, levulinated coumarin was selectively deprotected, resulting in chromogenic and fluorescent turn-on type signaling. The selective naked-eye detectable signaling of hydrazine was possible in the presence of representative metal ions and common anions in an aqueous environment.