| 1323485-48-8

• 分子结构分类: 有机化合物 - 叠烯 - 无环联烯
• CAS: 1323485-48-8
• 化学式: C₂₅H₄₈Sn
• 分子量: 467.366
• InChiKey: ONUGNOHFIPYPLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.91
• 重原子数：
  26
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.72
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-庚炔 、 (E)-1-iodo-1-tri(butyl)stannyl-1-hexene 在 copper(l) iodide 、 四(三苯基膦)钯 、 四丁基氢氧化铵 作用下， 以 四氢呋喃 、 水 、 异丙醇 为溶剂， 反应 0.17h， 以20%的产率得到(E)-tridec-5-en-7-yne
  参考文献：
  名称：

  Synthesis of (Z)-tributylstannyl enynes: systematic studies of Sonogashira cross-coupling reactions between (E)-1-iodovinyl-1-tributylstannanes and terminal acetylenes using amines or tetrabutylammonium hydroxide (TBAOH) as activator

  摘要：

  Sonogashira cross-coupling reactions involving (E)-iodo vinyl stannanes and terminal acetylenes were carried out in the presence of Pd(PPh(3))(4), Cul and several amines, affording (Z)-tributylstannyl enynes in moderate to good yields (62-91%). Utilizing the catalytic system containing Pd(PPh(3))(4) (5%), Cul (10%), and TBAOH (40% in aqueous media) as activator, better yields (72-91%) and lower reaction times were achieved. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.06.004

文献信息

• Synthesis of (Z)-tributylstannyl enynes: systematic studies of Sonogashira cross-coupling reactions between (E)-1-iodovinyl-1-tributylstannanes and terminal acetylenes using amines or tetrabutylammonium hydroxide (TBAOH) as activator
  作者：Carlos E.D. Nazario、Amanda S. Santana、Cristiane Y. Kawasoko、Carlos A. Carollo、Gabriela R. Hurtado、Luiz H. Viana、Sandro L. Barbosa、Palimécio G. Guerrero、Francisco A. Marques、Vânia B. Dabdoub、Miguel J. Dabdoub、Adriano C.M. Baroni

  DOI：10.1016/j.tetlet.2011.06.004

  日期：2011.8

  Sonogashira cross-coupling reactions involving (E)-iodo vinyl stannanes and terminal acetylenes were carried out in the presence of Pd(PPh(3))(4), Cul and several amines, affording (Z)-tributylstannyl enynes in moderate to good yields (62-91%). Utilizing the catalytic system containing Pd(PPh(3))(4) (5%), Cul (10%), and TBAOH (40% in aqueous media) as activator, better yields (72-91%) and lower reaction times were achieved. (C) 2011 Elsevier Ltd. All rights reserved.