diethyl 2,5-bis[4-[[(2S)-1-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]pyrrolidine-2-carbonyl]amino]anilino]benzene-1,4-dicarboxylate | 1246291-64-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: diethyl 2,5-bis[4-[[(2S)-1-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]pyrrolidine-2-carbonyl]amino]anilino]benzene-1,4-dicarboxylate
• CAS: 1246291-64-4
• 化学式: C₅₀H₆₆N₈O₁₂
• 分子量: 971.12
• InChiKey: IAISGQUNDGMSLA-OSFLMINUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  70
• 可旋转键数：
  22
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  252
• 氢给体数：
  6
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  diethyl 2,5-bis[4-[[(2S)-1-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]pyrrolidine-2-carbonyl]amino]anilino]benzene-1,4-dicarboxylate 在 盐酸 作用下， 以 乙醚 、 乙醇 为溶剂， 反应 15.0h， 生成
  参考文献：
  名称：

  Design and characterization of ferrocene–peptide–oligoaniline conjugates

  摘要：

  Ferrocene-peptide-oligoaniline conjugates were designed by the introduction of two ferrocene-peptide conjugates into a pi-conjugated phenylenediamine spacer to demonstrate the luminescent switching by changing the redox states of the pi-conjugated phenylenediamine moiety, wherein the self-aggregation of then-conjugated moiety was achieved in a higher concentration to induce the chirality organization with a red shift of the maximum emission wavelength. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.06.101
• 作为产物：
  描述：

  diethyl 2,5-bis(4-aminophenylamino)terephthalate 、 BOC-乙酰氨基异戊酸 在 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 1-羟基苯并三唑 作用下， 以 二氯甲烷 为溶剂， 反应 18.41h， 以91%的产率得到diethyl 2,5-bis[4-[[(2S)-1-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]pyrrolidine-2-carbonyl]amino]anilino]benzene-1,4-dicarboxylate
  参考文献：
  名称：

  Design and characterization of ferrocene–peptide–oligoaniline conjugates

  摘要：

  Ferrocene-peptide-oligoaniline conjugates were designed by the introduction of two ferrocene-peptide conjugates into a pi-conjugated phenylenediamine spacer to demonstrate the luminescent switching by changing the redox states of the pi-conjugated phenylenediamine moiety, wherein the self-aggregation of then-conjugated moiety was achieved in a higher concentration to induce the chirality organization with a red shift of the maximum emission wavelength. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.06.101

文献信息

• Design and characterization of ferrocene–peptide–oligoaniline conjugates
  作者：Toshiyuki Moriuchi、Nami Kikushima-Honda、Satoshi D. Ohmura、Toshikazu Hirao

  DOI：10.1016/j.tetlet.2010.06.101

  日期：2010.8

  Ferrocene-peptide-oligoaniline conjugates were designed by the introduction of two ferrocene-peptide conjugates into a pi-conjugated phenylenediamine spacer to demonstrate the luminescent switching by changing the redox states of the pi-conjugated phenylenediamine moiety, wherein the self-aggregation of then-conjugated moiety was achieved in a higher concentration to induce the chirality organization with a red shift of the maximum emission wavelength. (C) 2010 Elsevier Ltd. All rights reserved.