2-Fluoro-1-(4-methoxyphenyl)-4-(4-methylphenyl)benzene | 1228186-83-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Fluoro-1-(4-methoxyphenyl)-4-(4-methylphenyl)benzene
• 英文别名: 2-fluoro-1-(4-methoxyphenyl)-4-(4-methylphenyl)benzene
• CAS: 1228186-83-1
• 化学式: C₂₀H₁₇FO
• 分子量: 292.353
• InChiKey: LFNZGHDDLFPJFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  4-甲苯硼酸 、 4-甲氧基苯硼酸 、 1,4-二溴-2-氟苯 在 四(三苯基膦)钯 、 caesium carbonate 作用下， 以 1,4-二氧六环 为溶剂， 反应 14.0h， 以48%的产率得到2-Fluoro-1-(4-methoxyphenyl)-4-(4-methylphenyl)benzene
  参考文献：
  名称：

  通过二溴化fluorobenzenes的位点选择性的Suzuki-Miyaura交叉偶联反应官能化的氟化三联苯的合成

  摘要：

  通过二溴氟苯的定点Suzuki-Miyaura交叉偶联反应制备了多种氟化三联苯，例如1,2-二溴-3,5-二氟苯，1,4-二溴-2-氟苯，1,3-二溴-4-氟苯，和1,2-二溴-4-氟苯。

  DOI：

  10.1016/j.jfluchem.2012.12.003

文献信息

• One-pot synthesis of fluorinated terphenyls by site-selective Suzuki–Miyaura reactions of 1,4-dibromo-2-fluorobenzene
  作者：Muhammad Sharif、Muhammad Zeeshan、Sebastian Reimann、Alexander Villinger、Peter Langer

  DOI：10.1016/j.tetlet.2010.03.067

  日期：2010.5

  The Suzuki–Miyaura reaction of 1,4-dibromo-2-fluorobenzene with two equivalents of arylboronic acids gave fluorinated para-terphenyls. The reaction with 1 equiv of arylboronic acid resulted in site-selective formation of biphenyls. The one-pot reaction of 1,4-dibromo-2-fluorobenzene with two different arylboronic acids afforded fluorinated para-terphenyls containing two different terminal aryl groups

  1，4-二溴-2-氟苯与两当量的芳基硼酸的Suzuki-Miyaura反应产生了氟化的对三联苯。与1当量的芳基硼酸的反应导致联苯的位点选择性形成。1，4-二溴-2-氟苯与两种不同的芳基硼酸的一锅法反应得到含两个不同的末端芳基的氟化对-三联苯。
• POLYMERIZABLE COMPOUND HAVING TRIPLE BOND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20150376505A1

  公开（公告）日：2015-12-31

  To provide a liquid crystal compound having high polymerization reactivity, a high conversion ratio and high solubility in a liquid crystal composition, a polymerizable composition containing the compound, a liquid crystal composite prepared using the composition, and a liquid crystal display device including the composite. The liquid crystal display device prepared using the polymerizable composition containing the compound represented by formula (1): wherein, in formula (1), P 1 to P 6 are a polymerizable group; S 1 to S 6 are a single bond, alkylene or the like; a1, a3 and a4 are an integer from 0 to 4, a2 is an integer from 1 to 4; ring A 1 to ring A 4 are a divalent group derived from benzene, naphthalene, anthracene, pyrimidine, pyridine or the like; Z 1 to Z 3 are a single bond, alkylene or the like, and at least one of Z 1 , Z 2 and Z 3 is —C≡C—; and b1 is 0 or 1.

  为提供一种具有高聚合反应性、高转化率和高溶解度的液晶化合物，本发明提供了一种含有该化合物的可聚合组分、使用该组分制备的液晶复合物以及包括该复合物的液晶显示装置。使用式（1）所表示的化合物制备的聚合物化组分，其中，在式（1）中，P1到P6是可聚合基团；S1到S6是单键、烷基或类似物；a1、a3和a4是0至4的整数，a2是1至4的整数；环A1到环A4是由苯、萘、蒽、嘧啶、吡啶或类似物导出的二价基团；Z1到Z3是单键、烷基或类似物，其中至少一个为—C≡C—；b1为0或1。
• POLYMERIZABLE COMPOUND HAVING CONJUGATED BONDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20140312274A1

  公开（公告）日：2014-10-23

  Subject It is to provide a polymerizable compound having a high polymerization reactivity, a high conversion yield and a high solubility in a liquid crystal composition, a polymerizable composition including this compound, a liquid crystal composite prepared from this polymerizable composition and a liquid crystal display device containing this composite. Means for solving the Subject A compound represented by formula (1), the liquid crystal composition and the liquid crystal display device. In the formula, for example, ring A 1 , ring A 2 and ring A 4 are phenylene or cyclohexylene; Sp 1 and Sp 2 are a single bond or alkylene having 1 to 6 carbons; Z 1 and Z 2 are —CH═CH— or —C≡C—; a is 1, b is 0; and P 1 and P 2 are a polymerizable group.
• POLYMERIZABLE COMPOUND HAVING OXYGEN-CONTAINING FIVE-MEMBERED RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JNC CORPORATION

  公开号：US20150034871A1

  公开（公告）日：2015-02-05

  An object is to provide a polymerizable compound having high polymerization reactivity, a high conversion ratio and high solubility in a liquid crystal composition, a polymerizable composition containing the compound, a liquid crystal composite prepared from the composition, and a liquid crystal display device having the composite. A solution is a polymerizable compound represented by formula (1). In the formula, for example, P 1 and P 2 are —OCO—(CH 3 )C═CH 2 ; S 1 and S 2 are a single bond; ring A 1 , ring A 2 and ring A 3 are 1,4-phenylene; Z 1 , Z 2 and Z 3 are a single bond; two of G is —CH═ or —N═; and a is 0 or 1.
• LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION INCLUDING THE SAME AND LIQUID CRYSTAL DISPLAY INCLUDING THE LIQUID CRYSTAL COMPOSITION
  申请人：SAMSUNG DISPLAY CO., LTD.

  公开号：US20160083653A1

  公开（公告）日：2016-03-24

  A liquid crystal compound represented by Formula 1: