4-(3-O-benzyl-1,2-O-isopropylidene-α-D-xylotetrafuranos-4-yl)-1H-benzo[b][1,4]diazepine-3-carbonitrile | 1225468-75-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯二氮卓类
• 英文名称: 4-(3-O-benzyl-1,2-O-isopropylidene-α-D-xylotetrafuranos-4-yl)-1H-benzo[b][1,4]diazepine-3-carbonitrile
• CAS: 1225468-75-6
• 化学式: C₂₄H₂₃N₃O₄
• 分子量: 417.464
• InChiKey: UBILYRFESBMVMO-KAOXLYBCSA-N

反应信息

• 作为产物：
  描述：

  、 邻苯二胺 以 乙醇 为溶剂， 反应 2.0h， 以44%的产率得到4-(3-O-benzyl-1,2-O-isopropylidene-α-D-xylotetrafuranos-4-yl)-1H-benzo[b][1,4]diazepine-3-carbonitrile
  参考文献：
  名称：

  Synthesis of ReversedC-Nucleosides

  摘要：

  A number of C-nucleoside analogs of the D-furanose series were synthesized by using push-pull activated monosaccharide -dimethylaminomethyleneulose (1) as a precursor. Enaminoketone 1 was reacted with o-phenylenediamine, cyanamide, and dialkyl-3-oxoglutarates to obtain benzodiazepine nucleoside analog 2, reversed C-nucleoside analog with pyrimidine ring 3, and isophthalic acid derivative 4, respectively.

  DOI：

  10.1080/00397910903064849