2-amino-N-(2-methylpropyl)-3-phenylpropanamide | 1162643-13-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-amino-N-(2-methylpropyl)-3-phenylpropanamide
• CAS: 1162643-13-1
• 化学式: C₁₃H₂₀N₂O
• mdl: MFCD09941860
• 分子量: 220.315
• InChiKey: WQSJVUMFZCSEKE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.461
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• PEPTIDE AND METHOD FOR MANUFACTURING SAME
  申请人：AGC Inc.

  公开号：US20220119440A1

  公开（公告）日：2022-04-21

  A peptide having a fluoroalkyl group as its side chain and a method for producing, which comprises condensing a compound represented by the formula (6-2) or (6-4), where means that an asymmetric carbon atom has an absolute configuration of S or R, Rf is a C 1-30 alkyl group which is substituted with at least two fluorine atoms, and which may further be substituted with a halogen atom other than a fluorine atom (when the C 1-30 alkyl group is a C 2-30 alkyl group, it may have 1 to 5 etheric oxygen atoms between carbon atoms), and R 2 is a protecting group for the amino group, with a fluorinated amino acid having its carboxy group protected, an amino acid having its carboxy group protected, a fluorinated peptide having its C-terminal protected, or a peptide having its C-terminal protected.