3-isopropyl-2,5-dimethyl-pyrrole | 15345-60-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 3-isopropyl-2,5-dimethyl-pyrrole
• 英文别名: 3-Isopropyl-2,5-dimethyl-pyrrol；2,5-Dimethyl-3-isopropyl-pyrrol；2,5-dimethyl-3-propan-2-yl-1H-pyrrole
• CAS: 15345-60-5
• 化学式: C₉H₁₅N
• 分子量: 137.225
• InChiKey: IOQCZQBAWQNBHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-amino-4-methyl-3-pentanone 在 氢氧化钾 、 sodium acetate 、 溶剂黄146 作用下， 生成 3-isopropyl-2,5-dimethyl-pyrrole
  参考文献：
  名称：

  Nawa et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1955, vol. 75, p. 860,863

  摘要：

  DOI：

文献信息

• Plancher; Tanzi, Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1914, vol. <5> 23 II, p. 414
  作者：Plancher、Tanzi

  DOI：——

  日期：——
• INHIBITORS OF BACTERIAL GLYCOSYL TRANSFERASES
  申请人：President and Fellows of Harvard College

  公开号：US20180162862A1

  公开（公告）日：2018-06-14

  Described herein are compounds of Formula (I′), Formula (IA), Formulae (I)-(VII), pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The invention also provides pharmaceutical compositions of the compounds for human and veterinary use. Compounds of the present invention are useful for inhibiting bacterial growth and therefore are useful in treating and/or preventing bacterial infections. Methods of using the compounds for treating and/or preventing a bacterial infection in a subject are also described.