Synthesis of thiohydantoins under one-pot three-component solvent-free conditions
作者:Song Cao、Longjie Zhu、Chuanmeng Zhao、Xiuhong Tang、Huajun Sun、Xin Feng、Xuhong Qian
DOI:10.1007/s00706-007-0842-8
日期:2008.8
A direct and efficient one-pot three-component synthesis protocol was developed for the synthesis of thiohydantoins from readily and widely available substrates (isothiocyanates, ethyl chloroacetate, and amines) employing solvent-free conditions.