dimethyl 5-(3-(α-D-glucopyranosyl-[(1->4)-α-D-glucopyranosyl](4)-(1->4)-β-D-glucopyranosyloxy)propoxy)isophthalate | 1214935-70-2

• 分子结构分类: 有机化合物
• 英文名称: dimethyl 5-(3-(α-D-glucopyranosyl-[(1->4)-α-D-glucopyranosyl](4)-(1->4)-β-D-glucopyranosyloxy)propoxy)isophthalate
• CAS: 1214935-70-2
• 化学式: C₄₉H₇₆O₃₆
• 分子量: 1241.12
• InChiKey: NUICZRVJTKCTEM-MVQDCEBTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -12.03
• 重原子数：
  85.0
• 可旋转键数：
  24.0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.84
• 拓扑面积：
  556.96
• 氢给体数：
  19.0
• 氢受体数：
  36.0

反应信息

• 作为反应物：
  描述：

  dimethyl 5-(3-(α-D-glucopyranosyl-[(1->4)-α-D-glucopyranosyl](4)-(1->4)-β-D-glucopyranosyloxy)propoxy)isophthalate 在 一水合肼 作用下， 以 甲醇 为溶剂， 反应 6.0h， 以68%的产率得到5-(3-(α-D-glucopyranosyl-[(1->4)-α-D-glucopyranosyl](4)-(1->4)-β-D-glucopyranosyloxy)propoxy)isophthalic acid dihydrazide
  参考文献：
  名称：

  Glycodynamers: Dynamic Polymers Bearing Oligosaccharides Residues − Generation, Structure, Physicochemical, Component Exchange, and Lectin Binding Properties

  摘要：

  Dynamic glycopolymers have been generated by polycondensation through acylhydrazone formation between components bearing lateral bioactive oligosaccharide chains. They have been characterized as bottlebrush type by cryo-TEM and SANS studies. They present remarkable fluorescence properties whose emission wavelengths depend on the constitution of the polymer and are tunable by constitutional modification through exchange/incorporation of components, thus also demonstrating their dynamic character. Constitution-dependent binding of these glycodynamers to a lectin, peanut agglutinin, has been demonstrated.

  DOI：

  10.1021/ja9082733
• 作为产物：
  描述：

  dimethyl 5-(3-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl-[(1->4)-2,3,6-tri-O-acetyl-α-D-glucopyranosyl](4)-(1->4)-2,3,6-tri-O-acetyl-β-D-glucopyranosyloxy)propoxy)isophthalate 在 甲醇 、 potassium cyanide 作用下， 反应 24.0h， 以67%的产率得到dimethyl 5-(3-(α-D-glucopyranosyl-[(1->4)-α-D-glucopyranosyl](4)-(1->4)-β-D-glucopyranosyloxy)propoxy)isophthalate
  参考文献：
  名称：

  Glycodynamers: Dynamic Polymers Bearing Oligosaccharides Residues − Generation, Structure, Physicochemical, Component Exchange, and Lectin Binding Properties

  摘要：

  Dynamic glycopolymers have been generated by polycondensation through acylhydrazone formation between components bearing lateral bioactive oligosaccharide chains. They have been characterized as bottlebrush type by cryo-TEM and SANS studies. They present remarkable fluorescence properties whose emission wavelengths depend on the constitution of the polymer and are tunable by constitutional modification through exchange/incorporation of components, thus also demonstrating their dynamic character. Constitution-dependent binding of these glycodynamers to a lectin, peanut agglutinin, has been demonstrated.

  DOI：

  10.1021/ja9082733