2-hydroxy-4-oxo-decanoic acid | 666826-48-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 酮酸及其衍生物
• 英文名称: 2-hydroxy-4-oxo-decanoic acid
• 英文别名: 2-Hydroxy-4-oxo-decansaeure；2-Hydroxy-4-oxodecanoic acid
• CAS: 666826-48-8
• 化学式: C₁₀H₁₈O₄
• 分子量: 202.251
• InChiKey: ZFAIFQSJLNBVSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-hydroxy-4-oxo-decanoic acid 、 alkaline earth salt of/the/ methylsulfuric acid 、 alkaline earth salt of/the/ methylsulfuric acid 生成 庚酸
  参考文献：
  名称：

  Random Packs and Their Use in Modeling Heterogeneous Solid Propellant Combustion

  摘要：

  It is shown that random packs of spheres of various sizes can be constructed that model ammonium-perchloratein-binder propellants in the sense that both the size distributions and the packing fractions of industrial propellant packs can be matched, Strategies for dealing with fractional numbers of large particles are addressed, as are strategies for dealing with a large number of very fine particles (fine powder), Fine powder is necessary in a three-dimensional pack to achieve the required stoichiometric ratio of ammonium perchlorate to fuel binder, but is not necessary in a two-dimensional (disk) pack, Some preliminary calculations of the two-dimensional combustion field supported by a disk pack are presented, in which full coupling between the gas phase, the condensed phase, and the retreating nonplanar propellant surface is accounted for.

  DOI：

  10.2514/2.5820

文献信息

• SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS
  申请人：Genzyme Limited

  公开号：EP0620857A1

  公开（公告）日：1994-10-26
• US5686275A
  申请人：——

  公开号：US5686275A

  公开（公告）日：1997-11-11
• [EN] SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS
  申请人：GENZYME LIMITED

  公开号：WO1993013215A1

  公开（公告）日：1993-07-08

  (EN) A process for the production of a homochiral 2-hydroxy carboxylic acid or salt thereof corresponding to general formula (I), wherein R represents one of formulae (II), (III), (IV), (V), wherein R' represents straight- or branched-chain alkyl or phenyl optionally para-substituted with methyl, methoxy, nitro or amino; and R'' represents hydrogen, halogen or phenyl optionally para-substituted with methyl, methoxy, nitro or amino; and M represents hydrogen or a salt-forming moiety; characterised in that it comprises reducing a corresponding 2-keto carboxylic acid or salt thereof using a (R)- or (S)-2-oxo carboxylic acid dehydrogenase, $i(inter alia), is disclosed.(FR) L'invention décrit un procédé pour la production d'un acide 2-hydroxycarboxylique homochiral ou d'un sel de celui-ci correspondant à la formule générale (I), dans laquelle R représente une des formules (II), (III), (IV), (V), dans laquelle R' représente un alkyle ou un phényle à chaîne droite ou ramifiée éventuellement parasubstitué optionnellement avec un méthyle, méthoxy, nitro ou amino; et R'' représente l'hydrogène, un halogène ou un phényle éventuellement parasubstitué optionnellement avec un méthyle, méthoxy, nitro ou amino; et M représente l'hydrogène ou une fraction formant un sel; le procédé se caractérise par le fait qu'il comprend la réduction d'un acide 2-cétocarboxylique ou d'un sel de celui-ci au moyen d'une déshydrogénase d'acide (R)-ou (S)-2-oxocarboxylique, $i(inter alia).
• Random Packs and Their Use in Modeling Heterogeneous Solid Propellant Combustion
  作者：S. Kochevets、J. Buckmaster、T. L. Jackson、A. Hegab

  DOI：10.2514/2.5820

  日期：2001.7

  It is shown that random packs of spheres of various sizes can be constructed that model ammonium-perchloratein-binder propellants in the sense that both the size distributions and the packing fractions of industrial propellant packs can be matched, Strategies for dealing with fractional numbers of large particles are addressed, as are strategies for dealing with a large number of very fine particles (fine powder), Fine powder is necessary in a three-dimensional pack to achieve the required stoichiometric ratio of ammonium perchlorate to fuel binder, but is not necessary in a two-dimensional (disk) pack, Some preliminary calculations of the two-dimensional combustion field supported by a disk pack are presented, in which full coupling between the gas phase, the condensed phase, and the retreating nonplanar propellant surface is accounted for.