1-Decene-1-sulfonic acid, sodium salt | 41999-41-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 1-Decene-1-sulfonic acid, sodium salt
• 英文别名: (E)-dec-1-ene-1-sulfonic acid
• CAS: 41999-41-1
• 化学式: C₁₀H₂₀O₃S
• 分子量: 220.33
• InChiKey: SVDCMXMRTJEAHD-MDZDMXLPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  62.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Anionic polymers as toxin binders and antibacterial agents
  申请人：Kurtz Isabelle Bacon Caroline

  公开号：US20060029568A1

  公开（公告）日：2006-02-09

  The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of pendant acid functional groups which are directly attached to the polymer backbone or attached to the polymer backbone by a spacer group. The spacer group can have a length in the range from 0 to about 20 atoms. The toxin is, typically, an exotoxin secreted by a pathogenic microorganism, such as a bacterium.

  本发明涉及一种抑制动物中毒素的方法，例如人类，通过向动物施用具有多个悬垂酸性功能基团的聚合物的治疗有效量，这些基团直接连接到聚合物骨架或通过一个间隔基团连接到聚合物骨架。间隔基团的长度可以在0到大约20个原子的范围内。毒素通常是由致病微生物（例如细菌）分泌的外毒素。
• Anionic Polymers as Toxin Binders and Antibacterial Agents
  申请人：Bacon Kurtz Caroline Isabelle

  公开号：US20100172861A1

  公开（公告）日：2010-07-08

  The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of pendant acid functional groups which are directly attached to the polymer backbone or attached to the polymer backbone by a spacer group. The spacer group can have a length in the range from 0 to about 20 atoms. The toxin is, typically, an exotoxin secreted by a pathogenic microorganism, such as a bacterium.

  本发明涉及一种通过向动物，如人类，投放具有多个挂基酸功能团的聚合物的治疗有效量来抑制动物体内毒素的方法。这些挂基酸功能团直接连接到聚合物骨架上，或通过一个间隔基团连接到聚合物骨架上，该间隔基团的长度可在0至约20个原子范围内。该毒素通常是由致病微生物（如细菌）分泌的外毒素。
• DESFERRIOXAMINE-B SALTS AND THEIR USE AS ORALLY EFFECTIVE IRON CHELATORS
  申请人：CIBA-GEIGY AG

  公开号：EP0643690A1

  公开（公告）日：1995-03-22
• FORMULATIONS AND POLYMORPHIC FORMS OF DESFERRIOXAMINE AND THE PREPARATION THEREOF
  申请人：Novartis AG

  公开号：EP0944586A2

  公开（公告）日：1999-09-29
• ANIONIC POLYMERS AS TOXIN BINDERS AND ANTIBACTERIAL AGENTS
  申请人：GENZYME CORPORATION

  公开号：EP1189622B1

  公开（公告）日：2007-07-25