2,5-二甲基-2'-硝基-联苯基 | 102440-81-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,5-二甲基-2'-硝基-联苯基
• 英文名称: 2,5-dimethyl-2'-nitro-1,1'-biphenyl
• 英文别名: 2'-Nitro-2.5-dimethyl-diphenyl；2,5-Dimethyl-2'-nitro-biphenyl；1,4-Dimethyl-2-(2-nitrophenyl)benzene
• CAS: 102440-81-3
• 化学式: C₁₄H₁₃NO₂
• 分子量: 227.263
• InChiKey: WPGYNTMTAACTBY-UHFFFAOYSA-N

物化性质

• 沸点：
  90 °C(Press: 0.05 Torr)
• 密度：
  1.141±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,5-二甲基-2'-硝基-联苯基 生成 3-甲基-9H-芴
  参考文献：
  名称：

  The Synthesis of Some Model Compounds Related to Tetrahydrocannabinol

  摘要：

  DOI：

  10.1021/ja01504a042
• 作为产物：
  描述：

  对二甲苯 在 二氧化硫 、 碘 、 硝酸 、 铜 、 溶剂黄146 作用下， 生成 2,5-二甲基-2'-硝基-联苯基
  参考文献：
  名称：

  Y-TO-I WRAP: USE OF THE DISTAL SPONGIOSUM FOR HYPOSPADIAS REPAIR

  摘要：

  Purpose: Rather than resecting the distal spongiosum lateral to the open urethra for hypospadias, we mobilized this tissue with the urethral plate away from the corpora cavernosa, subsequently wrapping it around various types of urethroplasty to prevent fistula formation.Materials and Methods: The distal spongiosum was preserved and used for coverage in 25 hypospadias repairs in I year. We initially applied it in this manner when the distal spongiosum persisted as a pillar of healthy erectile tissue but later when the distal tissue appeared more fibrous in nature. The wrap was used to cover various types of urethroplasty, including advancement in 6 cases, tubularization in 10, flip-flap repair in 6 and an island onlay pedicle graft, in 3.Results: All patients have at least 1 year of followup. There has been no fistula formation or residual chordee. In 1 patient minor meatal retraction did not require a secondary procedure. Cosmetic results have been good.Conclusions: A distal wrap of corpus spongiosum may be used res avoid fistula formation without causing residual or recurrent curvature. It re-creates a nearly normal urethra in some cases.

  DOI：

  10.1016/s0022-5347(05)67673-2

文献信息

• Copper catalysed Gomberg-Bachmann-Hey reactions of arenediazonium tetrafluoroborates and heteroarenediazonium o-benzenedisulfonimides. Synthetic and mechanistic aspects
  作者：Achille Antenucci、Margherita Barbero、Stefano Dughera、Giovanni Ghigo

  DOI：10.1016/j.tet.2020.131632

  日期：2020.11

  heterobiaryls in good yields and in mild reaction conditions. A computational study of some key points of the reaction was performed. The results are coherent with the experimental data and confirm some aspects of the mechanism. The reaction free energies for the reduction in benzene by CuI of a set of 40 (hetero)arenediazonium tetrafluoroborates were calculated. Both the experiments and the calculations

  Gomberg-Bachmann-Hey反应在铜作为催化剂的情况下进行，以高收率和温和的反应条件产生联芳基或杂联芳基。对反应的一些关键点进行了计算研究。结果与实验数据一致，并证实了该机理的某些方面。计算了一组40个（杂）芳烯重氮四氟硼酸盐通过CuI还原苯所产生的反应自由能。实验和计算均表明，在与取代溶剂（甲苯，溴苯，硝基苯和苯甲醚）的偶联中，总是倾向于与邻位的结合。
• Water-soluble dye
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0187520A2

  公开（公告）日：1986-07-16

  A water-soluble dye, free from cellulose reactive groups, of the formula: wherein R' is -(CaH2aO)m(CbH2bO)nH, R2 is H or -(CaH2aO)m(CbH2bO)nH, or R1 & R2 together with the nitrogen atom form a morpholine ring a & b are different and from 1 to 8 m is from 1 to 10; n is from 0 to 9; X is the residue of a diazotisable amine Y is NR'R2 or non-chromophoric groups OR3 or NR3R4 in which R3 and R" are independently selected from H, alkyl and aryl. and Z is: wherein M is a monovalent cation, and an ink containing the dye suitable for use in an ink jet printing process.

  一种不含纤维素活性基团的水溶性染料，其式如下 其中 R' 是-(CaH2aO)m(CbH2bO)nH、 R2 是 H 或-(CaH2aO)m(CbH2bO)nH，或 R1 和 R2 与氮原子一起形成一个吗啉环 a 和 b 不相同，且在 1 到 8 之间 m 为 1 至 10 n 为 0 至 9； X 是可重氮胺的残余物 Y 是 NR'R2 或非色素基团 OR3 或 NR3R4，其中 R3 和 R "独立选自 H、烷基和芳基。 Z 是 其中 M 是一价阳离子，以及含有适合用于喷墨打印工艺的染料的墨水。
• Dari, Abdelmjid; Christiaens, Leon E.; Renson, Marcel J., Acta Chemica Scandinavica, 1993, vol. 47, # 2, p. 208 - 211
  作者：Dari, Abdelmjid、Christiaens, Leon E.、Renson, Marcel J.

  DOI：——

  日期：——
• US4726844A
  申请人：——

  公开号：US4726844A

  公开（公告）日：1988-02-23
• US4777248A
  申请人：——

  公开号：US4777248A

  公开（公告）日：1988-10-11