(E)-2-morpholino-3-phenyl-4-((triisopropylsilyl)oxy)but-3-enoic acid | 1329422-76-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: (E)-2-morpholino-3-phenyl-4-((triisopropylsilyl)oxy)but-3-enoic acid
• CAS: 1329422-76-5
• 化学式: C₂₃H₃₇NO₄Si
• 分子量: 419.637
• InChiKey: QJCKSBNJASXFDK-LTGZKZEYSA-N

反应信息

• 作为产物：
  描述：

  吗啉 、 triisopropyl((2-phenyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)oxy)silane 、 乙醛酸 以 六氟异丙醇 为溶剂， 反应 24.0h， 生成 (Z)-2-morpholino-3-phenyl-4-((triisopropylsilyl)oxy)but-3-enoic acid 、 (E)-2-morpholino-3-phenyl-4-((triisopropylsilyl)oxy)but-3-enoic acid
  参考文献：
  名称：

  Amphoteric α-Boryl Aldehydes

  摘要：

  A new class of stable molecules, alpha-boryl aldehydes, has been prepared from oxiranyl N-methyliminodiacetyl boronates by a 1,2-boryl migration with concomitant epoxide scission. A range of boryl imines, alkenes, alcohols, acids, enol ethers, enamides, and other functionalized boronic acid derivatives that are difficult or impossible to prepare using established protocols can be accessed from alpha-boryl aldehydes. The chemoselective transformations of these building blocks, including the facile synthesis of functionalized unnatural amino acids from silyloxy and amido vinyl boronates, attest to the potential of alpha-boryl aldehydes in chemical synthesis.

  DOI：

  10.1021/ja205910d