N-Methyl-m-propyloxyanilin | 59731-81-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-Methyl-m-propyloxyanilin
• 英文别名: N-methyl-3-propoxyaniline
• CAS: 59731-81-6
• 化学式: C₁₀H₁₅NO
• 分子量: 165.235
• InChiKey: GRSQLQMDSOQXEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-Methyl-m-propyloxyanilin 以91%的产率得到
  参考文献：
  名称：

  BENES L.; BOROVANSKY A.; CIZMARIK J.; SVEC P.; BEZAKOVA Z.; KOUBALIK B.; +, CS. FARM., 1975, 24, NO 2, 53-58

  摘要：

  DOI：
• 作为产物：
  描述：

  N-Methyl-N-(m-propyloxyphenyl)-p-toluolsulfonamid 、 硫酸 以59%的产率得到
  参考文献：
  名称：

  BENES L.; BOROVANSKY A.; CIZMARIK J.; SVEC P.; BEZAKOVA Z.; KOUBALIK B.; +, CS. FARM., 1975, 24, NO 2, 53-58

  摘要：

  DOI：

文献信息

• CANNABINERGIC NITRATE ESTERS AND RELATED ANALOGS
  申请人：Northeastern University

  公开号：US20160002195A1

  公开（公告）日：2016-01-07

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.

  本技术涉及新型大麻素硝酸酯及其类似物、制备方法、制药组合物及其作为药物、药理工具和/或生物标志物的使用方法。这些新型大麻素硝酸酯化合物提供了治疗各种疾病和医学障碍的有用药物。
• Process to make a conductive composition of a fluorinated polymer which contains polyaniline
  申请人：Arkema France

  公开号：EP1428857B1

  公开（公告）日：2007-01-31
• P38 AND JNK MAPK INHIBITORS FOR THE TREATMENT AND PROPHYLAXIS OF DEGENERATIVE DISEASES OF THE NERVOUS SYSTEM
  申请人：ALLINKY BIOPHARMA

  公开号：US20170107230A1

  公开（公告）日：2017-04-20

  p38 and JNK mitogen activated protein (MAP) kinase al losteric inhibitors are useful for treatment and/or prophylaxis of degenerative diseases of the nervous system. Compounds are used in a method for treatment and/or prophylaxis of the diseases and for use in therapy in general. The compounds bind to the region composed of amino acids at positions 170-199 of Mitogen-activated protein kinase 14 (Uniprot accession nr Q16539 or SEQ ID No 1) and/or Mitogen-activated protein kinase 11 (Uniprot accession nr Q15759 or SEQ ID No 2), SEQ ID NO.1 and SEQ ID NO.2 being the amino acid sequences of MAPK14 (ρ38α) and MAPK11 (ρ38β), respectively. The specific region composed of amino acids at positions 170-199 is herein disclosed as SEQ ID HO.4 for Mitogen-activated protein kinase 14 and SEQ ID NO.5 for Mitogen-activated protein kinase 11 and are believed to be new inhibitory binding sites.
• Cannabinergic Nitrate Esters And Related Analogs
  申请人：Northeastern University

  公开号：US20170210728A1

  公开（公告）日：2017-07-27

  The present technology relates to novel cannabinergic nitrate esters and related analogs, process of preparation, pharmaceutical compositions and their methods of use as medicaments, pharmacological tools and/or biomarkers. The novel cannabinergic nitrate ester compounds provide medicaments useful in treating a variety of diseases and medical disorders.
• US9580400B2
  申请人：——

  公开号：US9580400B2

  公开（公告）日：2017-02-28