4-[4-({[(Hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methoxy)-phenylazo]-N,N-bis-({[(hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methyl)-benzamide | 281189-56-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 4-[4-({[(Hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methoxy)-phenylazo]-N,N-bis-({[(hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methyl)-benzamide
• CAS: 281189-56-8
• 化学式: C₂₈H₃₅N₉O₁₁
• 分子量: 673.64
• InChiKey: HBRDPYXWKPKICF-ULIFNZDWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.19
• 重原子数：
  48.0
• 可旋转键数：
  16.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  263.18
• 氢给体数：
  6.0
• 氢受体数：
  13.0

反应信息

• 作为反应物：
  描述：

  4-[4-({[(Hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methoxy)-phenylazo]-N,N-bis-({[(hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methyl)-benzamide 在 铁粉 作用下， 生成 4-[4-({[(Hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methoxy)-phenylazo]-N,N-bis-({[(hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methyl)-benzamide
  参考文献：
  名称：

  Microbial Growth Regulation Using Photoresponsive Siderophore

  摘要：

  一种含有可逆顺式/反式可控偶氮苯骨架的新型三羟基铁载体，已经过黄杆菌的生物活性测试。单体形式的顺式铁（III）复合物显示出与天然铁载体铁氧胺B相当的显著活性，但二聚体形式的反式铁（III）复合物则没有活性。

  DOI：

  10.1246/cl.2000.872
• 作为产物：
  描述：

  4-[4-({[(Hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methoxy)-phenylazo]-N,N-bis-({[(hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methyl)-benzamide 反应 20.0h， 以50%的产率得到4-[4-({[(Hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methoxy)-phenylazo]-N,N-bis-({[(hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methyl)-benzamide
  参考文献：
  名称：

  Synthesis of a novel azobenzene-based trihydroxamate siderophore and photoregulation of its ferric complex structure

  摘要：

  In order to develop an artificial photoresponsive siderophore by utilizing the photo-isomerization of an azobenzene group, a novel trihydroxamate siderophore based on an azobenzene skeleton was synthesized. The 1:1 and 2:2 stoichiometry of the ferric complex can be almost perfectly regulated reversibly by irradiation with UV and visible light, respectively. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00175-1