1-(3',4'-dimethoxyphenyl)-6,7-dimethoxynaphthalene | 109980-42-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-(3',4'-dimethoxyphenyl)-6,7-dimethoxynaphthalene
• 英文别名: (3,4-Dimethoxyphenyl)-6,7-dimethoxynaphthalene；1-(3,4-dimethoxyphenyl)-6,7-dimethoxynaphthalene
• CAS: 109980-42-9
• 化学式: C₂₀H₂₀O₄
• 分子量: 324.376
• InChiKey: BRJOQEBIQWDTBJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  36.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,2-bis(3,4-dimethoxybenzoyl)ethane 在 lithium aluminium tetrahydride 、 乙醚 、 溶剂黄146 、 苯 作用下， 生成 1-(3',4'-dimethoxyphenyl)-6,7-dimethoxynaphthalene
  参考文献：
  名称：

  Traverso, Gazzetta Chimica Italiana, 1959, vol. 89, p. 1818,1823

  摘要：

  DOI：

文献信息

• [Cu]/NFSI-Mediated Cascade Diels–Alder Radical Annulations Using Norbornene as H-Acceptor under Redox-Neutral Conditions
  作者：Zhengyu Xu、Jianqiao Weng、Li Wei、Tianming Huang、Jie Wu、Zhiyuan Chen

  DOI：10.1021/acs.joc.3c02202

  日期：2024.2.16

  An oxidative cascade [4 + 2] radical cycloaddition/dehydroaromatization reaction of aryl alkenes to access α-aryl substituted naphthalenes under redox-neutral conditions was achieved. This reaction was found to require the addition of [Cu] catalyst along with stoichiometric concentrations of NFSI as a trigger of radical series of steps. Norbornene (NBE), rather than the conventional oxidant, manifested

  在氧化还原中性条件下，实现了芳基烯烃的氧化级联[4+2]自由基环加成/脱氢芳构化反应，得到α-芳基取代的萘。人们发现该反应需要添加[Cu]催化剂以及化学计量浓度的NFSI作为自由基系列步骤的触发因素。降冰片烯 (NBE)，而不是传统的氧化剂，在此过程中作为 H 受体表现出了最佳的性能。本文的结果可能会为过渡金属催化脱氢 C-H 活化方案提供令人鼓舞的见解。
• Cerium(IV) Ammonium Nitrate Induced Dimerization of Methoxystyrenes
  作者：Vijay Nair、V. Sheeba、Sreeletha B. Panicker、Tesmol G. George、Roshini Rajan、Lakshmi Balagopal、M. Vairamani、S. Prabhakar

  DOI：10.1016/s0040-4020(00)00054-5

  日期：2000.4

  4-Methoxystyrene 1 underwent dimerization to 1,4-diphenylbutane derivatives 5 and 6 in presence of CAN in methanol. But in ethanol the same reaction afforded a tetralone derivative along with 5 and 6. 3,4-Dimethoxystyrene 10 underwent dimerization in presence of CAN in methanol to afford acyclic as well as cyclic products. 3,4,5-Trimethoxystyrene 12 in presence of CAN in methanol afforded only the cyclized dimers, the tetralone 21 and the tetralin derivative 22. (C) 2000 Elsevier Science Ltd. All rights reserved.