bis-[2-(2-propyliminomethyl)phenolato-N,O]cobalt(II) | 15379-69-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: bis-[2-(2-propyliminomethyl)phenolato-N,O]cobalt(II)
• 英文别名: bis(N-isopropylsalicylaldimine)cobalt(II)；bis(N-propylsalicylideneamino-N,O)cobalt(II)
• CAS: 15379-69-8；41754-09-0
• 化学式: C₂₀H₂₄CoN₂O₂
• 分子量: 383.416
• InChiKey: YXPBRVPJPJBKFN-NVFNPILPSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  水杨醛 以 甲醇 为溶剂， 反应 10.17h， 生成 bis-[2-(2-propyliminomethyl)phenolato-N,O]cobalt(II)
  参考文献：
  名称：

  Synthesis, characterization, crystal structure and DNA, HSA-binding studies of four Schiff base complexes derived from salicylaldehyde and isopropylamine

  摘要：

  Four new Schiff base complexes (NiL2, CoL2, CuL2 and ZnL2) (HL: ((E)-2-((isopropylamino) methyl) phenol) were synthesized and characterized by CHN elemental analysis, FT-IR and single crystal X-ray diffraction technique. The crystallographic data reveal that in all complexes the metal centers are four-coordinated by two phenolate oxygen and two imine nitrogen atoms of two moles of Schiff base ligand HL and geometry around the metal center in all of them is distorted tetrahedral. In addition, H-1 and C-13 NMR techniques were employed for characterization of diamagnetic ZnL2 complex. The binding affinity of complexes with DNA (fish sperm DNA, FS-DNA) and Human Serum Albumin (HSA) were investigated using fluorescence quenching, chemometrics, UV-Vis spectroscopy, viscosity measurements and molecular docking methods. The obtained results revealed that the DNA and HSA affinity for binding to complexes are in the following order: CuL2 > ZnL2 > CoL2 > NiL2 and NiL2 > ZnL2 > CuL2 > CoL2. The distance between complexes and HSA was obtained based on the Forster's theory of non-radiative energy transfer. The computational molecular docking results showed that H-bond interactions, hydrophobic interactions, pi-pi stacking and pi-cation interactions have dominant role in the stability of HSA-ML2 (M: Cu, Co, Ni and Zn). The computational docking and viscosity results suggest that all metal complexes interact with DNA presumably by the groove binding mechanism. (c) 2017 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2017.05.035

文献信息

• Synthesis and crystal structure of cobalt(II) Schiff base precursor for cobalt oxide thin film by thermal chemical vapor deposition
  作者：P. Sravanthi、C. Chandrakala、S. Raj Bharath、M.G. Johnson、S. Arokiasamy、K.S. Nagaraja、B. Jeyaraj

  DOI：10.1016/j.poly.2015.12.033

  日期：2016.5

  The tetrahedral Schiff base complex bis(N-isopropylsalicylaldimine)cobalt(II) [Co(saliprn)2] (CSI) was prepared by template method. The complex was characterized by FT-IR, mass spectroscopy, TG/DTA and single crystal X-ray structure determination analysis. The dynamic TG analysis showed that the complex is completely volatile. The equilibrium vapor pressure of the complex was studied by non-isothermal

  摘要采用模板法制备了四面体席夫碱配合物双（N-异丙基水杨醛亚胺）钴（II）[Co（saliprn）2]（CSI）。通过FT-IR，质谱，TG / DTA和单晶X射线结构测定分析对复合物进行了表征。动态TG分析表明该络合物是完全挥发性的。通过非等温和等温热重蒸腾技术研究了配合物的平衡蒸气压，温度范围为474–514K。配合物的Ea（48.4 kJ mol-1）和ΔHsub（111.54 kJ mol-1）得到了蒸气压（Pe）的温度依赖性的表达式。通过在氮气氛下使用不同的非等温加热速率，通过热重技术研究了钴（II​​）配合物的热行为。发现该络合物是挥发性的，并用于热化学气相沉积中，以在二氧化硅基底上开发纳米晶氧化钴薄膜。通过XRD和SEM对这些纳米晶体薄膜进行了分析，证实了几乎没有碳的Co3O4相的存在。
• Cobalt complexes with bidentate (NO) versus monodentate (N) salicylaldimine ligands: Syntheses, crystal structures, and comparison in bioactivity profile against bacterial, fungal, and cancer cells and activities on wheat germination indices
  作者：Ereny S. Williem、Ahmed Amro、Ahmed B. M. Ibrahim、S. Abd Elkhalik、Florian Meurer、Michael Bodensteiner、S. M. Abbas

  DOI：10.1002/aoc.7601

  日期：2024.8

  respectively. Both complexes and the control offered 100% germination for a drought-resistive wheat cultivar, but complex C1 offered only 95% wheat germination under drought conditions. For a drought-sensitive wheat cultivar, the control, complex C1, and complex C2 offered 90%, 85%, and 90% germination under normal irrigation and 95%, 100%, and 95% germination under drought.

  制备了钴(II)与一元双配位2-((异丙基亚氨基)甲基)苯酚}和中性单配位2-((吡啶-3-亚氨基)甲基)苯酚}配体的两种配合物。配体未以固体形式分离，配合物分别为 [Co(L 1 ) 2 ] C1 和 [Co (HL 2 ) 2 Cl 2 ] C2 是从含有氯化钴 (II)、水杨醛和相应胺的溶液中获得的。晶体学研究证实配合物 C1 和 C2 中的钴分别通过 N 2 O 2 和 N 2 Cl 2 供体原子进行四重配位。此外，这些配合物在斜方晶系 Pbca (C1) 和单斜晶系 I2/a (C2) 空间群中结晶。对于两种真菌，DMSO 中的复合物 (20 mg/mL) 仅在白色念珠菌菌株中诱导直径为 11 毫米和 15 毫米的抑制区，但两性霉素 B 却能抑制这种真菌 21 毫米。 DMSO 中的所有复合物 (20 mg/mL) 均针对枯草芽孢杆菌、金黄色葡萄球菌、大肠杆菌和铜绿假单胞菌菌株进行了测试。复合物
• Diehl, H.; Chao, T. S., Iowa State College Journal of Science, 1947, vol. 22, p. 126 - 128
  作者：Diehl, H.、Chao, T. S.

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Co: SVol.B1, 91, page 198 - 200
  作者：

  DOI：——

  日期：——
• Bis(N-2-propylsalicylideneamino-N,O)cobalt(II)
  作者：Y. Elerman、M. Kabak、M. N. Tahir

  DOI：10.1107/s0108270196007111

  日期：1996.10.15

  The title complex, bis[2-(2-propyliminomethyl)phenolato-N,O]cobalt(II), [Co(C10H12NO)(2)], has two chelating Schiff base ligands coordinating through their N and O atoms to give a tetrahedral geometry distorted mainly by reduction of the chelate O-Co-N angles and by expansion of the N-Co-N angle because of steric hindrance of the isopropyl substituents. The Co-O bonds [mean 1.906 (5) Angstrom] are shorter than the Co-N bonds [mean 1.992(8) Angstrom].