ethyl-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy)[2,3-b](11,12-benzo-1,4,7,10,13,16-hexaoxacyclooctadeca-11-ene)-2,3-dideoxy-α-D-glucopyranoside | 260414-06-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: ethyl-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy)[2,3-b](11,12-benzo-1,4,7,10,13,16-hexaoxacyclooctadeca-11-ene)-2,3-dideoxy-α-D-glucopyranoside
• CAS: 260414-06-0
• 化学式: C₃₆H₅₂O₂₀
• 分子量: 804.797
• InChiKey: OYAVOPGXOWYMKV-IZMYAETLSA-N

反应信息

• 作为反应物：
  描述：

  ethyl-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy)[2,3-b](11,12-benzo-1,4,7,10,13,16-hexaoxacyclooctadeca-11-ene)-2,3-dideoxy-α-D-glucopyranoside 在 4-二甲氨基吡啶 、 sodium methylate 作用下， 以 吡啶 、 甲醇 为溶剂， 反应 30.0h， 生成 ethyl-2-(β-D-galactopyranosyloxy) [2,3-b](11,12-benzo-1,4,7,10,13,16-hexaoxacyclooctadeca-11-ene)-2,3-dideoxy-α-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of ethoxy-linked pseudo-disaccharides incorporating a crown ether macrocycle and lectin recognition

  摘要：

  Six ethoxy-linked pseudo-disaccharides incorporating a non-reducing D-galactopyranosyl residue and a glucose bearing an 18-crown-6-ether were synthesized by the trichloracetimidate method. Deprotection left four novel structures from which two were tested against the galactose-specific lectin Kluyveromyces bulgaricus. Their minimum inhibitory concentration (MIC) was in the same order of magnitude as compared to previously prepared oligosaccharides without spacer. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(99)00194-9
• 作为产物：
  描述：

  2,3,4,6-tetra-O-acetyl-D-galactopyranosyl trichloroacetimidate 、 (2-hydroxy-ethyl) [2,3-b](11,12-benzo-1,4,7,10,13,16-hexaoxacyclooctadeca-11-ene)-4,6-O-benzylidene-2,3-dideoxy-α-D-glucopyranoside 在 三氟化硼乙醚 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以22%的产率得到ethyl-2-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyloxy) [2,3-b](11,12-benzo-1,4,7,10,13,16-hexaoxacyclooctadeca-11-ene)-4,6-O-benzylidene-2,3-dideoxy-α-D-glucopyranoside
  参考文献：
  名称：

  Synthesis of ethoxy-linked pseudo-disaccharides incorporating a crown ether macrocycle and lectin recognition

  摘要：

  Six ethoxy-linked pseudo-disaccharides incorporating a non-reducing D-galactopyranosyl residue and a glucose bearing an 18-crown-6-ether were synthesized by the trichloracetimidate method. Deprotection left four novel structures from which two were tested against the galactose-specific lectin Kluyveromyces bulgaricus. Their minimum inhibitory concentration (MIC) was in the same order of magnitude as compared to previously prepared oligosaccharides without spacer. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0008-6215(99)00194-9