1-(1-octynyl)-2-iodobenzene | 502157-83-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(1-octynyl)-2-iodobenzene
• 英文别名: 1-iodo-2-(1-octynyl)benzene；1-iodo-2-(oct-1-ynyl)benzene；1-iodo-2-(oct-1-yn-1-yl)benzene；1-Iodo-2-oct-1-ynylbenzene
• CAS: 502157-83-7
• 化学式: C₁₄H₁₇I
• 分子量: 312.193
• InChiKey: MVUFXPLZPLCHFL-UHFFFAOYSA-N

物化性质

• 沸点：
  343.4±25.0 °C(predicted)
• 密度：
  1.39±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-(1-octynyl)-2-iodobenzene 在 四丁基醋酸铵 、 palladium diacetate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以40%的产率得到5,10-dihexyl-indeno[2,1-a]indene
  参考文献：
  名称：

  Diaceno[a,e]pentalenes from Homoannulations of o-Alkynylaryliodides Utilizing a Unique Pd(OAc)₂/n-Bu₄NOAc Catalytic Combination

  摘要：

  A heterogeneous catalytic system, Pd(OAc)(2)/n-Bu4NOAc, for the efficient synthesis of diaceno[a,e)pentalenes via a tandem Pd catalytic cycle is reported. The catalytic partner n-Bu4NOAc played indispensable and versatile roles, acting as both the media for recovering active Pd(0) species and their stabilizer. A series of new diaceno[a,dpentalenes were obtained in moderate to high yields, among which the octacydic dianthracenopentalene was found to be highly emissive.

  DOI：

  10.1021/ol502440d
• 作为产物：
  描述：

  2-(oct-1-yn-1-yl)aniline 在 对甲苯磺酸 、 potassium iodide 、 sodium nitrite 作用下， 以 水 、 乙腈 为溶剂， 反应 2.17h， 以80%的产率得到1-(1-octynyl)-2-iodobenzene
  参考文献：
  名称：

  Synthesis of tetracyclic chromenones via platinum(ii) chloride catalysed cascade cyclization of enediyne–enones

  摘要：

  报道了 PtCl2 催化烯二炔烯酮体系级联环化生成四环色烯酮的过程，该过程一步完成两个连续的高区域选择性 6-endoâdig 环化，形成两个新的 CâC 键和两个新的环，收率极高。根据分离出的中间产物，提出了这种转化的机理。

  DOI：

  10.1039/c3ob41911h

文献信息

• C(sp2)-C(sp) and C(sp)-C(sp) Coupling Reactions Catalyzed by Oxime-Derived Palladacycles
  作者：Diego A. Alonso、Carmen Nájera、Ma Carmen Pacheco

  DOI：10.1002/adsc.200303067

  日期：2003.9

  4′-dichlorobenzophenone, is an efficient pre-catalyst for the copper- and amine-free Sonogashira coupling between terminal acetylenes and aryl iodides and aryl and vinyl bromides achieving turnover numbers (TON) of up to 72000. Catalyst 8a has also been shown as a effective promoter for the sila-Sonogashira coupling between 1-(trimethylsilyl)alkynes and aryl iodides and bromides in the presence of CuI or

  衍生自4,4'-二氯二苯甲酮的肟衍生的氯桥式Palladacycle 8a是末端乙炔与芳基碘化物之间的无铜和无胺Sonogashira偶联的有效预催化剂，达到了营业额（TON ）最高可达72000。在CuI或Bu 4存在的情况下，催化剂8a还被证明是1-（三甲基甲硅烷基）炔烃与芳基碘化物和溴化物之间sila-Sonogashira偶联的有效促进剂。NBr作为助催化剂。这种配合物还能在室温下以TONs高达1000的效率有效地催化NMP中1-炔烃之间的均偶联反应（Glaser型偶联）。所有反应均可在空气中进行，并在极低的负载条件下使用试剂级化学物质，证明了肟衍生的palladacycles的多功能性和高活性。
• En Route to Archimedene:  Total Synthesis of <i>C</i>₃<i>_h</i>-Symmetric [7]Phenylene
  作者：Dirk Bruns、Hirokazu Miura、K. Peter C. Vollhardt、Amnon Stanger

  DOI：10.1021/ol027482z

  日期：2003.2.1

  [reaction: see text] The total synthesis of C(3)(h)-symmetric [7]phenylene has been accomplished by triple cobalt-catalyzed cycloisomerization of an appropriate nonayne. Its spectral data are in accord with the expectations for a triply angularly fused system, but its calculated heat of formation suggests the presence of a destabilizing sigma effect relative to its D(3)(h) isomer. The molecule constitutes

  [反应：见正文] C（3）（h）-对称的[7]亚苯基的总合成已通过适当的壬炔的三重钴催化环异构化完成。它的光谱数据符合三重角度熔融系统的预期，但是其计算出的形成热表明相对于其D（3）（h）异构体，存在不稳定的sigma效应。该分子构成迄今合成的阿基米德的最大亚结构。
• Pd-Catalyzed double carbopalladation/<i>syn</i>-insertion cascade reactions toward medium-size sulfoximine heterocycles
  作者：Longji Dai、Jianjun Yuan、Cui Wu、Zhiyuan Chen

  DOI：10.1039/d1cc00846c

  日期：——

  With the application of Ac in sulfoximine as a protecting group (PG) and MeOH as a de-PG agent, Pd-catalyzed multicomponent reactions were developed to access indene-fused medium-size sulfoximine heterocycles.

  利用Ac在亚砜中作为保护基（PG）和MeOH作为去PG试剂，开发了Pd催化的多组分反应，以获得茚烯融合的中等大小的亚砜杂环化合物。
• Exfoliated polystyrene-clay nanocomposite comprising star-shaped polymer
  申请人：——

  公开号：US20040068038A1

  公开（公告）日：2004-04-08

  A nanocomposite made with an inorganic layered material and a star-shaped polystyrene that can be blended with normal linear polystyrene is disclosed. The inorganic layered material can have an exfoliated structure, substantially exfoliated, or intercalated structure. The exfoliated structure can result in significantly improved physical properties, even with only a very low content of clay. The invention is also directed to a process that can be used to make the compositions of the present invention. In one embodiment, a physical mixture of clay and star polymer is prepared and then the mixture is heated for several hours, preferably under high-shear mixing, to increase the rate of exfoliation, after which mostly inexpensive commodity linear polystyrene polymer completes the composition.

  本发明揭示了一种由无机层状材料和星形聚苯乙烯制成的纳米复合材料，可与普通线性聚苯乙烯混合。无机层状材料可以具有剥离结构、大部分剥离结构或插层结构。剥离结构可以导致显着改善物理性能，即使只有非常低的粘土含量也是如此。本发明还涉及一种可用于制备本发明组分的工艺。在一种实施例中，制备粘土和星形聚合物的物理混合物，然后将混合物加热数小时，最好在高剪切混合下，以增加剥离速率，之后大多数廉价的商品线性聚苯乙烯聚合物完成组成。
• EXFOLIATED POLYSTYRENE-CLAY NANOCOMPOSITE COMPRISING STAR-SHAPED POLYMER
  申请人：——

  公开号：US20030220434A1

  公开（公告）日：2003-11-27

  A nanocomposite made with an inorganic layered material and a star-shaped polystyrene that can be blended with normal linear polystyrene is disclosed. The inorganic layered material can have an exfoliated structure, substantially exfoliated, or intercalated structure. The exfoliated structure can result in significantly improved physical properties, even with only a very low content of clay. The invention is also directed to a process that can be used to make the compositions of the present invention. In one embodiment, a physical mixture of clay and star polymer is prepared and then the mixture is heated for several hours, preferably under high-shear mixing, to increase the rate of exfoliation, after which mostly inexpensive commodity linear polystyrene polymer completes the composition.

  本发明涉及一种由无机层状材料和星形聚苯乙烯制成的纳米复合材料，可以与普通线性聚苯乙烯混合。该无机层状材料可以具有剥离结构、基本剥离结构或插层结构。即使只含有非常少的粘土，剥离结构也可以导致显著改善物理性能。本发明还涉及一种可用于制备本发明组合物的方法。在一种实施方式中，制备粘土和星形聚合物的物理混合物，然后在高剪切混合下加热数小时以增加剥离速率，之后大部分廉价的商品线性聚苯乙烯聚合物完成组成。