Se-methyl 1-(p-chlorophenyl)-1-(4-pyridyl)ethane-1-selenocarboxylate | 1235721-18-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Se-methyl 1-(p-chlorophenyl)-1-(4-pyridyl)ethane-1-selenocarboxylate
• 英文别名: Se-Methyl I+/--(4-chlorophenyl)-I+/--methyl-4-pyridineethaneselenoate；Se-methyl 2-(4-chlorophenyl)-2-pyridin-4-ylpropaneselenoate
• CAS: 1235721-18-2
• 化学式: C₁₅H₁₄ClNOSe
• 分子量: 338.695
• InChiKey: UKGVBYSGWBMPFC-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  一氧化碳 、 4-(1-(4-chlorophenyl)ethyl)pyridine 、 碘甲烷 在 正丁基锂 、 六甲基磷酰三胺 、 selenium 作用下， 反应 0.5h， 以41%的产率得到Se-methyl 1-(p-chlorophenyl)-1-(4-pyridyl)ethane-1-selenocarboxylate
  参考文献：
  名称：

  Regioselectivity of Selenium-Mediated Carbonylation of Organolithium Compounds with Carbon Monoxide

  摘要：

  Regioselectivity of selenium-mediated carbonylation of organolithium compounds with carbon monoxide has been investigated. The reactions of lithium enolates of 2,2-dicyclohexyl aldehyde and 1,1-dicyclohexylpropane-2-one with selenium and carbon monoxide afforded the corresponding selenocarbonates by carbonylation at the enolate oxygen as the main product. Carbonylation of nitrogen-containing heterocycles can give either C- or N-carbonylation product, but diphenyl(4-pyridyno)methane, imidazole, and pyrazole afford only corresponding carbamoselenoates via N-carbonylation.

  DOI：

  10.1080/10426501003773456