| 1395941-61-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• CAS: 1395941-61-3
• 化学式: C₈₄H₈₂O₁₅S₂
• 分子量: 1395.7
• InChiKey: CDYRVERPJAYZAD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.71
• 重原子数：
  101.0
• 可旋转键数：
  39.0
• 环数：
  13.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  169.81
• 氢给体数：
  0.0
• 氢受体数：
  15.0

反应信息

• 作为反应物：
  描述：

  在 sodium azide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 6.0h， 以71%的产率得到
  参考文献：
  名称：

  Multivalent Nanofibers of a Controlled Length: Regulation of Bacterial Cell Agglutination

  摘要：

  Control of the size and shape of molecular assemblies on the nanometer scale in aqueous solutions is very important for the regulation of biological functions. Among the well-defined supramolecular structures of organic amphiphiles, one-dimensional nanofibers have attracted much attention because of their potential applications in biocompatible materials. Although much progress has been made in the field of self-assembled nanofobers, the ability to control the fiber length remains limited. The approach for control of the fiber length presented herein overcomes this limitation through the coassembly of amphiphilic rod-coil molecules in which the crystallinity of the aromatic segment can be regulated by pi-pi stacking interactions. The introduction of carbohydrate segments into the fiber exterior endows the nanofibers with the ability to adhere to bacterial cells. Notably, the fiber length systematically regulates the agglutination and proliferation of bacterial cells exposed to these fibers.

  DOI：

  10.1021/ja306802m
• 作为产物：
  描述：

  、 对甲苯磺酰氯 在 吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以47%的产率得到
  参考文献：
  名称：

  Multivalent Nanofibers of a Controlled Length: Regulation of Bacterial Cell Agglutination

  摘要：

  Control of the size and shape of molecular assemblies on the nanometer scale in aqueous solutions is very important for the regulation of biological functions. Among the well-defined supramolecular structures of organic amphiphiles, one-dimensional nanofibers have attracted much attention because of their potential applications in biocompatible materials. Although much progress has been made in the field of self-assembled nanofobers, the ability to control the fiber length remains limited. The approach for control of the fiber length presented herein overcomes this limitation through the coassembly of amphiphilic rod-coil molecules in which the crystallinity of the aromatic segment can be regulated by pi-pi stacking interactions. The introduction of carbohydrate segments into the fiber exterior endows the nanofibers with the ability to adhere to bacterial cells. Notably, the fiber length systematically regulates the agglutination and proliferation of bacterial cells exposed to these fibers.

  DOI：

  10.1021/ja306802m