2,2,6,6-tetramethyl-3-methylene-5-morpholinylmethyl-4-hydroxypiperidine-N-oxyl | 133828-27-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 2,2,6,6-tetramethyl-3-methylene-5-morpholinylmethyl-4-hydroxypiperidine-N-oxyl
• CAS: 133828-27-0
• 化学式: C₁₅H₂₅N₂O₃
• 分子量: 281.375
• InChiKey: JQXYMIBSUCPEKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.28
• 重原子数：
  20.0
• 可旋转键数：
  2.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  52.68
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  吗啉 、 2,2,6,6-tetramethyl-3,5-dimethylene-4-oxopiperidine-1-oxyl 以 正己烷 为溶剂， 生成 2,2,6,6-tetramethyl-3-methylene-5-morpholinylmethyl-4-hydroxypiperidine-N-oxyl
  参考文献：
  名称：

  Kinetics, mechanism, and reactivity of an activated carbon-carbon double bond in nitroxyl radicals and their diamagnetic analog in interaction with some secondary amines and polyethyleneimine

  摘要：

  Routes for the reaction of a conjugated methylene group of nitroxyl radicals (NR) with secondary amines were suggested and analyzed. Kinetic parameters of the limiting step of this reaction for the NR-amine and diamagnetic analog of NR-amine systems were estimated. The effect of the medium on these reactions was examined. The specific behavior of polyethyleneimine in the reaction with activated methylene groups of 2,2,6,6-tetramethyl-3,5-dimethylene-4-oxopiperidine-1-oxyl was demonstrated.

  DOI：

  10.1007/bf01431300