2,4,5,6,7-Pentamethyl-indol | 1203-56-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 2,4,5,6,7-Pentamethyl-indol
• 英文别名: 2,4,5,6,7-pentamethyl-indole；2,4,5,6,7-pentamethyl-1H-indole
• CAS: 1203-56-1
• 化学式: C₁₃H₁₇N
• 分子量: 187.285
• InChiKey: IAQFZAORSVWIHZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

文献信息

• Asymmetric Friedel-Crafts Alkylations Catalyzed By Bifunctional Cinchona Alkaloids
  申请人：Deng Li

  公开号：US20090203913A1

  公开（公告）日：2009-08-13

  In certain embodiments, the present invention relates to methods for asymmetric Friedel-Crafts alkylation catalyzed by bifunctional cinchona alkaloids. In certain embodiments, the catalyst is a 6′-OH cinchona alkaloid. In certain embodiments, the electrophile is an α-ketoester or aldehyde. In certain embodiments, the nucleophile is an aromatic heterocycle. In certain embodiments, the nucleophile is an aromatic N-containing heterocycle. In certain embodiments, the nucleophile is an indole. In certain embodiments, the methods of the invention are relatively insensitive to concentration, temperature, air and moisture.
• US8367847B2
  申请人：——

  公开号：US8367847B2

  公开（公告）日：2013-02-05
• US8791262B2
  申请人：——

  公开号：US8791262B2

  公开（公告）日：2014-07-29