5,10,15,20-tetra-p-chloromethylphenylporphyrin | 85857-14-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 5,10,15,20-tetra-p-chloromethylphenylporphyrin
• 英文别名: 5,10,15,20-tetrakis(p-chloromethylphenyl)porphyrin；meso tetrakis(4-chlorobenzyl)porphyrin；tetrakis(p-chloromethylphenyl) porphyrin
• CAS: 85857-14-3
• 化学式: C₄₈H₃₄Cl₄N₄
• 分子量: 808.637
• InChiKey: UCYYQMBJEDSVMX-PJEPRTEXSA-N

物化性质

• 密度：
  1.345±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  14.28
• 重原子数：
  56.0
• 可旋转键数：
  8.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  57.36
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  5,10,15,20-tetra-p-chloromethylphenylporphyrin 、 三苯基膦 以 N,N-二甲基甲酰胺 为溶剂， 反应 48.0h， 生成
  参考文献：
  名称：

  Phosphoniumyl cationic porphyrins Self-aggregation origin from [pi ][ndash ][pi ] and cation[ndash ][pi ] interactions

  摘要：

  四种含膦盐残基的阳离子卟啉在卟啉平面边缘的电光谱特性在含水和有机溶剂相中得到研究。纯水、无机和有机电解质存在下膦酰卟啉的电子光谱进行了比较，并提出膦酰卟啉的自聚集是由形成H聚集的π-π相互作用引起的，而加入NaCl后通过卟啉平面和边缘膦盐阳离子的阳离子-π相互作用，这种几何结构可转变为J聚集。1H NMR光谱提供证据表明，高极化膦盐阳离子与高极化卟啉π表面有强相互作用。

  DOI：

  10.1039/a703965d
• 作为产物：
  描述：

  5,10,15,20-tetrakis-(4-hydroxymethylphenyl)porphyrin 在 氯化亚砜 作用下， 反应 10.0h， 以100%的产率得到5,10,15,20-tetra-p-chloromethylphenylporphyrin
  参考文献：
  名称：

  Synthesis and preliminary dna-interaction studies of a new cationic porphyrin

  摘要：

  DOI：

  10.1016/s0040-4039(00)97720-7

文献信息

• A new route of water soluble porphyrins: phosphonium and ammonium type cationic porphyrins and self-assembly
  作者：Ren-Hua Jin、Shinya Aoki、Kensuke Shima

  DOI：10.1039/cc9960001939

  日期：——

  From a precursor porphyrin, tetrakis(p-chloromethylphenyl) porphyrin, the novel phosphoniumyl and ammoniumyl cationic porphyrins are synthesized, and the unusual spontaneous assembly for the two cationic porphyrins is discussed.

  从四(对氯甲基苯基)卟啉出发，合成了新型的磷鎓型和铵型阳离子卟啉，并探讨了这两种阳离子卟啉的特殊自组装现象。
• Highly luminescent, biocompatible ytterbium(<scp>iii</scp>) complexes as near-infrared fluorophores for living cell imaging
  作者：Yingying Ning、Juan Tang、Yi-Wei Liu、Jing Jing、Yuansheng Sun、Jun-Long Zhang

  DOI：10.1039/c8sc00259b

  日期：——

  β-fluorinated Yb3+ complexes display high NIR luminescence (quantum yields up to 23% and 13% in dimethyl sulfoxide and water, respectively) and have higher stabilities and prolonged decay lifetimes (up to 249 μs) compared to the β-non-fluorinated counterparts. This renders the β-fluorinated Yb3+ complexes as a new class of biological optical probes in both steady-state imaging and time-resolved fluorescence lifetime

  在这里，我们报告近红外（NIR）活细胞成像的生物相容性Yb 3+配合物的设计和合成。这些β-氟化的Yb 3+络合物在可见光（Soret带）或红色区（Q带）处激发时，显示出高NIR发光（在二甲基亚砜和水中的量子产率分别高达23％和13％），并具有与β-非氟化物相比，具有更高的稳定性和更长的衰减寿命（高达249μs）。这使得β-氟化的Yb 3+络合物在稳态成像和时间分辨荧光寿命成像（FLIM）中均成为一类新型的生物光学探针。NIR共聚焦荧光图像显示强而特异性的细胞内Yb 3+当生物相容的Yb 3+复合物被吸收到活细胞中时发出发光信号。重要的是，FLIM测量显示细胞内寿命分布在100到200μs之间，从而可以有效区分细胞自发荧光，并提供了高信噪比，这首先在NIR区域得到了证明。这些结果证明了近红外镧系配合物作为近红外稳态荧光和时间分辨荧光寿命成像的生物探针的前景。
• Water-soluble block copolymer and production method therefor
  申请人：KAWAMURA INSTITUTE OF CHEMICAL RESEARCH

  公开号：EP1400555A1

  公开（公告）日：2004-03-24

  A water-soluble block copolymer having a mass average molecular weight of 2500 to 800000 and comprising, within a molecule, a poly(ethylene imine) block unit and a poly(N-propionylethylene imine) block unit is a novel linear or star-shaped water-soluble block copolymer.

  一种水溶性嵌段共聚物的质量平均分子量为 2500 至 800000，分子中包含一个聚（乙烯亚胺）嵌段单元和一个聚（N-丙酰基乙烯亚胺）嵌段单元，是一种新型的线型或星型水溶性嵌段共聚物。
• ORGANIC-INORGANIC COMPOSITE NANOFIBER, ORGANIC-INORGANIC COMPOSITE STRUCTURE AND METHOD FOR PRODUCING THOSE
  申请人：KAWAMURA INSTITUTE OF CHEMICAL RESEARCH

  公开号：EP1717273A1

  公开（公告）日：2006-11-02

  The present invention relates to an organic-inorganic hybrid nanofiber formed from a crystalline polymer filament made of a polymer having a straight-chain polyethyleneimine skeleton, and a silica covering the aforementioned crystalline polymer filament, a structure formed from the aforementioned organic-inorganic hybrid nanofiber, and a method for producing the same.

  本发明涉及一种由具有直链聚乙烯亚胺骨架的聚合物制成的结晶聚合物长丝和覆盖在上述结晶聚合物长丝上的二氧化硅形成的有机-无机杂化纳米纤维、由上述有机-无机杂化纳米纤维形成的结构以及生产该结构的方法。
• Absorption and fluorescence properties of aryl substituted porphyrins in different media
  作者：Serap Seyhan Bozkurt、Melek Merdivan、Sevda Ayata

  DOI：10.1016/j.saa.2009.11.019

  日期：2010.2

  Absorption and fluorescence properties of aryl substituted porphyrins, 5,10,15,20-tetra-4-oxy(aceticacid)phenylporphyrin (TAPP), 5,10,15,20-tetra-(4-phenoxyphenyl) porphyrin (TPPP), 5,10,15,20-tetra-(3-bromo-4-hydroxyphenyl) porphyrin (TBHPP), and 5,10,15,20-tetra-p-chloromethylphenyl porphyrin (CMPP) were investigated. The UV/vis absorption, fluorescence and excited spectra as the fluorescence quantum yields and fluorescence lifetimes for the compounds were measured in organic solvents (chloroform (CHCl3), tetrahydrofuran (THF)) and immobilized media (PVC film, sol-gel matrix). The fluorescence quantum yields of TAPP and TPPP were higher than the others. The fluorescence lifetimes of all studied porphyrin derivates were found to be fifty percent lower and their fluorescence intensities were increased fifty percent more in both of immobilized mediums, as compared to organic solvents. (C) 2009 Elsevier B.V. All rights reserved.