1,4,7,10,13,17,20,23,26,29-decaoxacyclodotriacontane-14,16,30,32-tetraone | 503157-08-2

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酯类和类似物
• 英文名称: 1,4,7,10,13,17,20,23,26,29-decaoxacyclodotriacontane-14,16,30,32-tetraone
• 英文别名: 1,4,7,10,13,17,20,23,26,29-Decaoxacyclodotriacontane-14,16,30,32-tetrone
• CAS: 503157-08-2
• 化学式: C₂₂H₃₆O₁₄
• 分子量: 524.519
• InChiKey: CBYAIJFXMKDGOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  36
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  161
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为反应物：
  描述：

  1,4,7,10,13,17,20,23,26,29-decaoxacyclodotriacontane-14,16,30,32-tetraone 在 4-乙酰氨基苯磺酰叠氮 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 二氯甲烷 为溶剂， 以82%的产率得到15,31-bisdiazo-1,4,7,10,13,17,20,23,26,29-decaoxacyclodotriacontane-14,16,30,32-tetraone
  参考文献：
  名称：

  Reactions of macrocyclic rhodium carbenoids: regioselective synthesis of indol-3-yl macrocyclic lactones and cryptands

  摘要：

  A wide variety of new macrocyclic diazocarbonyl compounds with various spacers was synthesized. Macrocyclic rhodium(H) carberioid insertion with various substituted indoles was performed to afford regioselectively, indol-3-yl macrocyclic di- or tetralactones (C3-alkylation). Double carberioid insertion was also performed to afford indolyl cryptand molecules. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.11.102
• 作为产物：
  描述：

  四甘醇单苄醚 在 palladium on activated charcoal 氢气 作用下， 以 四氢呋喃 、 乙醇 、 甲苯 、 苯 为溶剂， 反应 61.0h， 生成 1,4,7,10,13,17,20,23,26,29-decaoxacyclodotriacontane-14,16,30,32-tetraone
  参考文献：
  名称：

  Fullerene Ylidene Malonate Supramolecular Triads

  摘要：

  DOI：

  10.1002/1099-0690(200210)2002:20<3385::aid-ejoc3385>3.0.co;2-v

文献信息

• C2 Symmetrical double chromophores: cooperativity effects in lanthanide ion complexationElectronic supplementary information (ESI) available: chemical shifts for diastereoisomeric pairs 4/5 in C6D6 solutions (300 MHz). See http://www.rsc.org/suppdata/ob/b4/b403494e/
  作者：Dario Pasini、Pier Paolo Righetti、Michele Zema

  DOI：10.1039/b403494e

  日期：——

  We describe the synthesis and characterization of C2 symmetrical double chromophores, in which two identical chromophores are linked through ethylene glycol spacers of increasing lengths. The complexation ability of the trans stereopure form for each diastereoisomeric pair showed how the two chromophores, when the spacer unit is comprised of a diethylene or a triethylene glycol moiety, are able to interact in a positive way, stabilizing the resulting complexes when compared with single chromophore analogous compounds.

  我们描述了C2对称双发色团的合成和特性，其中两个相同的发色团通过长度不断增加的乙二醇间隔物连接。对于每个非对映异构体对，反式立体纯形式的络合能力表明，当间隔单元由二乙二醇或三乙二醇部分组成时，两个发色团能够以积极的方式相互作用，与单发色团类似化合物相比，稳定了所得络合物。
• Selective Syntheses of Novel Polyether Fullerene Multiple Adducts
  作者：Zhiguo Zhou、David I. Schuster、Stephen R. Wilson

  DOI：10.1021/jo034542l

  日期：2003.10.1

  We have applied a modified macrocyclic tether approach to control multiple additions to C-60. The technique of He-3 NMR was used to confirm the selective formation of specific C-60 multiple adducts by the macrocyclic tether approach. An oligoglycol was used as a flexible linker to produce macrocyclic polyether-linked malonates 5, 6, 8, and 9 under solid-liquid PTC (phase-transfer-catalysis) conditions. The formation of a single C60 tris-adduct, 3, from macrocyclic malonate 1 and (HeC60)-He-3-C-@ was proven by He-3 NMR. Similarly, multiple additions to C-60 of macrocyclic polyether malonate 5 gave C-60 bis-adduct 10 selectively, while the reaction of C-60 with macrocyclic malonate 8 gave bis-adducts 11 and 12. A similar process with macrocyclic malonate 6 gave tris-adduct 13 with high selectivity as well. Saponification of these C-60 multiple adducts gives the corresponding polyacids that are potentially useful in biological applications. Macrocyclic polyether fullerenes are a new class of ionophores, which could be interesting for molecular recognition and for the development of biosensors.