4-乙基-6-羟基己醛 | 61822-29-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 4-乙基-6-羟基己醛
• 英文名称: 4-ethyl-6-hydroxy-hexanal
• 英文别名: 4-Ethyl-6-hydroxyhexanal
• CAS: 61822-29-5
• 化学式: C₈H₁₆O₂
• 分子量: 144.214
• InChiKey: XGYGHXMCMADXEK-UHFFFAOYSA-N

物化性质

• 沸点：
  226.4±23.0 °C(Predicted)
• 密度：
  0.925±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,1-二溴-2-(E-丙烯基)环丙烷 在 二异丁基氢化铝 作用下， 以 正己烷 为溶剂， 生成 4-乙基-6-羟基己醛
  参考文献：
  名称：

  Kienzle,F., Synthetic Communications, 1976, vol. 6, p. 465 - 468

  摘要：

  DOI：

文献信息

• Method for producing optical fiber having formyl groups on core surface thereof
  申请人：IBIDEN CO., LTD.

  公开号：EP0575973A2

  公开（公告）日：1993-12-29

  The present invention is directed to a method for producing an optical fiber having formyl groups on a core surface. In one embodiment, a plastic optical fiber having formyl groups on a core surface is obtained by immersing the core surface of the plastic optical fiber in a treating solution containing at least a 0.5 to 40 mM alkali metal hydroxide and a compound having formyl groups in water or lower alcohol solvent. In the other embodiment, a plastic optical fiber having formyl groups on a core surface is obtained by introducing a vic-diol group, a primary hydroxyl group or an alkenyl group on the core surface, and then oxidizing it. Turbidity on the core surface of the optical fiber thus obtained is minimized, thereby reducing the transmittance losses of light.

  本发明涉及一种生产纤芯表面带有甲酰基的光纤的方法。在一个实施例中，通过将塑料光纤的芯表面浸入至少含有 0.5 至 40 mM 碱金属氢氧化物和具有甲酰基的化合物的水或低级醇溶剂的处理溶液中，获得芯表面具有甲酰基的塑料光纤。在另一个实施方案中，通过在芯表面引入沧二醇基、伯羟基或烯基，然后将其氧化，可获得芯表面具有甲酰基的塑料光纤。这样得到的光纤芯表面的浊度最小，从而减少了光的透射损失。
• Modified hyaluronidases and uses in treating hyaluronan-associated diseases and conditions
  申请人：Frost Gregory I.

  公开号：US20120171153A1

  公开（公告）日：2012-07-05

  Provided are combinations, compositions and kits containing a hyaluronan degrading enzyme, such as a soluble hyaluronidase, for treatment of hyaluronan-associated conditions, diseases and disorders. In one example, the products include an additional agent or treatment. Such products can be used in methods for administering the products to treat the hyaluronan-associated diseases and conditions, for example, hyaluronan-associated cancers, for example, hyaluronan-rich tumors. The methods include administration of the hyaluronan degrading enzyme composition alone or in combination with other treatments. Also provided are methods and compositions for providing sustained treatment effects in hyaluronan-associated diseases and conditions.
• PH20 Polypeptide Variants, Formulations And Uses Thereof
  申请人：Wei Ge

  公开号：US20130302275A1

  公开（公告）日：2013-11-14

  Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof.
• COMPANION DIAGNOSTIC FOR ANTI-HYALURONAN AGENT THERAPY AND METHODS OF USE THEREOF
  申请人：Jiang Ping

  公开号：US20140348817A1

  公开（公告）日：2014-11-27

  Methods and diagnostic agents for identification of subjects for cancer treatment with an anti-hyaluronan agent, such as a hyaluronan-degrading enzyme, are provided. Diagnostic agents for the detection and quantification of hyaluronan in a biological sample and monitoring cancer treatment with an anti-hyaluronan agent, for example a hyaluronan-degrading enzyme, are provided. Combinations and kits for use in practicing the methods also are provided.
• US5354574A
  申请人：——

  公开号：US5354574A

  公开（公告）日：1994-10-11