methyl 3-chloromethyl-pyrazine-2-carboxylate | 870787-02-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: methyl 3-chloromethyl-pyrazine-2-carboxylate
• 英文别名: Methyl 3-chloromethylpyrazine-2-carboxylate；methyl 3-(chloromethyl)pyrazine-2-carboxylate
• CAS: 870787-02-3
• 化学式: C₇H₇ClN₂O₂
• 分子量: 186.598
• InChiKey: UIAJGBFHDXOSBH-UHFFFAOYSA-N

物化性质

• 沸点：
  308.9±42.0 °C(Predicted)
• 密度：
  1.319±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  52.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  methyl 3-chloromethyl-pyrazine-2-carboxylate 在 cesium fluoride 作用下， 以 六甲基磷酰三胺 、 二甲基亚砜 为溶剂， 反应 0.67h， 以9%的产率得到methyl 3-fluoromethyl-pyrazine-2-carboxylate
  参考文献：
  名称：

  SUBSTITUTED PYRAZINECARBOXYLIC ACID ANILIDE DERIVATIVES OR SALTS THEREOF, INTERMEDIATES OF THE SAME, PESTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF

  摘要：

  公开号：

  EP1757595B1
• 作为产物：
  描述：

  3-甲基吡嗪-2-羧酸甲酯 在 N-氯代丁二酰亚胺 、 过氧化苯甲酰 作用下， 以 氯仿 为溶剂， 反应 30.0h， 以52%的产率得到methyl 3-chloromethyl-pyrazine-2-carboxylate
  参考文献：
  名称：

  SUBSTITUTED PYRAZINECARBOXYLIC ACID ANILIDE DERIVATIVES OR SALTS THEREOF, INTERMEDIATES OF THE SAME, PESTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF

  摘要：

  公开号：

  EP1757595B1

文献信息

• Substituted Pyrazinecarboxylic Acid Anilde Dervatives Or Salts Thereof, Intermediates Of The Same, Pesticides for Agricultural And Horticultural Use, and Usage Thereof
  申请人：Furuya Takashi

  公开号：US20080064708A1

  公开（公告）日：2008-03-13

  Substituted pyrazinecarboxylic acid anilide derivatives represented by the general formula (I) or salts thereof; intermediates of them; pesticides (such as insecticides and acaricides) for agricultural and horticultural use, containing the compounds as the active ingredient; and usage thereof: wherein R 1 is H, C 1-6 alkyl, halo C 1-6 alkyl, or the like; R 2 is halogeno, C 1-6 alkyl, or the like; G is C 2-10 alkyl or the like; Z is oxygen or sulfur; X's are each independently H, halogeno, or the like; Y's are each independently H, halogeno, cyano, or the like; and m and n are each an integer of 1 to 3.

  代表通式（I）的取代吡嗪羧酸苯酰胺衍生物或其盐；它们的中间体；农业和园艺用杀虫剂（如杀虫剂和螨虫剂），其含有该化合物作为活性成分；以及它们的用途：其中R1为H，C1-6烷基，卤代C1-6烷基或类似物；R2为卤代，C1-6烷基或类似物；G为C2-10烷基或类似物；Z为氧或硫；X分别为H，卤代或类似物；Y分别为H，卤代，氰基或类似物；m和n均为1至3的整数。
• Substituted pyrazinecarboxylic acid anilide derivatives or salts thereof, intermediates of the same, pesticides for agricultural and horticultural use, and usage thereof
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：US08269045B2

  公开（公告）日：2012-09-18

  Substituted pyrazinecarboxylic acid anilide derivatives represented by the general formula (I) or salts thereof; intermediates of them; pesticides (such as insecticides and acaricides) for agricultural and horticultural use, containing the compounds as the active ingredient; and usage thereof: wherein R1 is H, C1-6 alkyl, halo C1-6 alkyl, or the like; R2 is halogeno, C1-6 alkyl, or the like; G is C2-10 alkyl or the like; Z is oxygen or sulfur; X's are each independently H, halogeno, or the like; Y's are each independently H, halogeno, cyano, or the like; and m and n are each an integer of 1 to 3.

  代表通式（I）或其盐的取代吡嗪羧酸苯酰胺衍生物；它们的中间体；用作农业和园艺用途的杀虫剂（如杀虫剂和杀螨剂），其含有该化合物作为活性成分；以及它们的用途：其中R1为H，C1-6烷基，卤代C1-6烷基或类似物；R2为卤代基，C1-6烷基或类似物；G为C2-10烷基或类似物；Z为氧或硫；X分别为H，卤代基或类似物；Y分别为H，卤代基，氰基或类似物；m和n均为1至3的整数。
• US7910735B2
  申请人：——

  公开号：US7910735B2

  公开（公告）日：2011-03-22
• US8269045B2
  申请人：——

  公开号：US8269045B2

  公开（公告）日：2012-09-18
• SUBSTITUTED PYRAZINECARBOXYLIC ACID ANILIDE DERIVATIVES OR SALTS THEREOF, INTERMEDIATES OF THE SAME, PESTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP1757595B1

  公开（公告）日：2013-11-20