4-乙氧基苯甲酸 | 619-83-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 4-乙氧基苯甲酸
• 英文名称: cyclohexa-2,5-diene-1,4-dicarboxylic acid
• 英文别名: Δ^2.5-Dihydroterephthalsaeure；Cyclohexa-2,5-dien-1,4-dicarbonsaeure；1.4-Dicarboxy-2,5-cyclohexadien；2,5-Cyclohexadiene-1,4-dicarboxylic acid
• CAS: 619-83-0
• 化学式: C₈H₈O₄
• 分子量: 168.149
• InChiKey: FKHZOILQVUFMTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2917209090

反应信息

• 作为反应物：
  描述：

  4-乙氧基苯甲酸 在 氧气 作用下， 生成 对苯二甲酸
  参考文献：
  名称：

  SEMI-SYNTHETIC TEREPHTHALIC ACID VIA MICROORGANISMS THAT PRODUCE MUCONIC ACID

  摘要：

  本发明提供了一种非自然存在的微生物有着至少一个外源核酸编码的足量表达黏酸途径酶以产生黏酸的黏酸途径微生物。黏酸途径包括以下酶的选择：β-酮巯基硫酰酶、β-酮己二酸-CoA水解酶、β-酮己二酸-CoA转移酶、β-酮己二酸-CoA连接酶、2-富马酰乙酸还原酶、2-富马酰乙酸脱氢酶、顺式-3-羟基-4-己烯二酸脱水酶、2-富马酰乙酸氨基转移酶、2-富马酰乙酸氨基氧化还原酶、顺式-3-氨基-4-己烯二酸脱氨酶、β-酮己二酸烯醇内酯水解酶、黏酸内酯异构酶、黏酸环异构酶、β-酮己二酸-CoA脱氢酶、3-羟基己二酰-CoA脱水酶、2,3-脱氢己二酰-CoA转移酶、2,3-脱氢己二酰-CoA水解酶、2,3-脱氢己二酰-CoA连接酶、黏酸还原酶、2-马来酰乙酸还原酶、2-马来酰乙酸脱氢酶、顺式-3-羟基-4-己烯二酸脱水酶、2-马来酰乙酸氨基转移酶、2-马来酰乙酸氨基氧化还原酶、顺式-3-氨基-4-己烯二酸脱氨酶和黏酸顺/反异构酶。还提供了其他黏酸途径酶。此外，还提供了生产黏酸的方法。

  公开号：

  US20110124911A1
• 作为产物：
  描述：

  对苯二甲酸 、 硫酸 生成 4-乙氧基苯甲酸
  参考文献：
  名称：

  在洛杉矶部署先进的公共交通系统 (APTS) 技术：总结和分析

  摘要：

  本文首先介绍了在洛杉矶都会区部署智能交通系统 (ITS) 技术的主要参与者。然后，该文件报告了主要先进公共交通系统 (APTS) 项目的当地部署情况，特别强调了蓬勃发展的洛杉矶智能班车示范项目。此外，论文围绕APTS技术在洛杉矶大都市区的部署，分析了一些技术、政治、财务等问题。

  DOI：

  10.1002/atr.5670360107

文献信息

• Reactive polymer-supporting porous film for battery seperator and use thereof
  申请人：Uetani Yoshihiro

  公开号：US20060257727A1

  公开（公告）日：2006-11-16

  The invention provides a reactive polymer-supporting porous film for use as a battery separator which comprises a porous substrate film and a partially crosslinked reactive polymer supported on the porous substrate film, the partially crosslinked reactive polymer being obtained by the reaction of a crosslinkable polymer having at least one reactive group selected from the group consisting of 3-oxetanyl group and epoxy group in the molecule with a polycarboxylic acid. The reactive polymer-supporting porous film for use as a battery separator has a separator and electrodes sufficiently bonded to each other and low inner resistance so that it is suitably used for production of battery excellent in high rate performance. Further, the invention provides a method of producing a battery which comprises placing the electrode/reactive polymer-supporting porous film layered body in a battery container; introducing an electrolytic solution containing a cationic polymerization catalyst into the battery container thereby bonding the porous film and the electrodes together.

  本发明提供一种反应性聚合物支持多孔膜，用于作为电池隔膜，包括多孔基底膜和部分交联的反应性聚合物支持在多孔基底膜上，所述部分交联的反应性聚合物是通过交联性聚合物与多羧酸反应而得到的，所述交联性聚合物在分子中至少具有3-氧杂环基团和环氧基团中的一种反应性基团。作为电池隔膜使用的反应性聚合物支持多孔膜，具有足够紧密结合的隔膜和电极以及低内阻，因此适用于生产高速性能优异的电池。此外，本发明还提供一种电池的制造方法，其中包括将电极/反应性聚合物支持多孔膜层状体放置在电池容器中；向电池容器中引入含有阳离子聚合催化剂的电解液，从而将多孔膜和电极粘合在一起。
• REACTIVE POLYMER-SUPPORTING POROUS FILM FOR BATTERY SEPARATOR AND USE THEREOF
  申请人：Uetani Yoshihiro

  公开号：US20110232081A1

  公开（公告）日：2011-09-29

  A reactive polymer-supporting porous film is provided as a battery separator which comprises a porous substrate film and a partially crosslinked reactive polymer supported on the porous substrate film. The partially crosslinked reactive polymer is obtained by the reaction of a crosslinkable polymer having at least one group selected from the 3-oxetanyl group and epoxy group reactive with a polycarboxylic acid. The reactive polymer-supporting porous film has a separator and electrodes sufficiently bonded to each other and with low inner resistance suitably used for production of battery excellent in high rate performance. Further, provided is a method of producing a battery which comprises placing the electrode/reactive polymer-supporting porous film layered body in a battery container; introducing an electrolytic solution containing a cationic polymerization catalyst into the battery container thereby bonding the porous film and electrodes together.

  提供一种反应性聚合物支撑多孔膜作为电池隔膜，包括一个多孔基底膜和部分交联的反应性聚合物支撑在多孔基底膜上。部分交联的反应性聚合物是通过交联聚合物与至少具有3-氧杂环基团和环氧基团之一的可反应羧酸反应而得到的。反应性聚合物支撑多孔膜具有足够粘结的隔膜和电极，内阻低，适用于生产高速性能优异的电池。此外，还提供了一种制造电池的方法，包括将电极/反应性聚合物支撑多孔膜层状体放置在电池容器中；向电池容器中引入含有阳离子聚合催化剂的电解质溶液，从而将多孔膜和电极粘结在一起。
• MICROORGANISMS AND PROCESSES FOR PRODUCING TEREPHTHALIC ACID AND ITS SALTS
  申请人：Genomatica, Inc.

  公开号：US20150080547A1

  公开（公告）日：2015-03-19

  The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy) phosphonate (2H3M40P) pathway, p-toluate pathway, and/or terephthalate pathway. The invention additionally provides methods of using such organisms to produce 2H3M40P, p-toluate or terephthalate. Also provided herein are processes for isolating bio-based aromatic carboxylic acid, in particular, p-toluic acid or terephthalic acid, from a culture medium, wherein the processes involve contacting the culture medium with sufficient carbon dioxide (C02) to lower the pH of the culture medium to produce a precipitate comprised of the aromatic carboxylic acid.

  本发明提供了具有（2-羟基-3-甲基-4-氧代丁氧基）膦酸酯（2H3M40P）途径、对甲基苯甲酸途径和/或对苯二甲酸途径的非天然微生物生物体。本发明还提供了使用这种生物体生产2H3M40P、对甲基苯甲酸或对苯二甲酸的方法。本文还提供了从培养基中分离生物基芳香族羧酸，特别是对甲苯酸或对苯二甲酸的工艺，其中所述工艺涉及将培养基与足够的二氧化碳（C02）接触以降低培养基的pH值，从而产生由芳香族羧酸组成的沉淀物。
• Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
  申请人：GENOMATICA, INC.

  公开号：US10041093B2

  公开（公告）日：2018-08-07

  The invention provides a non-naturally occurring microbial organism having a muconate pathway having at least one exogenous nucleic acid encoding a muconate pathway enzyme expressed in a sufficient amount to produce muconate. The muconate pathway including an enzyme selected from the group consisting of a beta-ketothiolase, a beta-ketoadipyl-CoA hydrolase, a beta-ketoadipyl-CoA transferase, a beta-ketoadipyl-CoA ligase, a 2-fumarylacetate reductase, a 2-fumarylacetate dehydrogenase, a trans-3-hydroxy-4-hexendioate dehydratase, a 2-fumarylacetate aminotransferase, a 2-fumarylacetate aminating oxidoreductase, a trans-3-amino-4-hexenoate deaminase, a beta-ketoadipate enol-lactone hydrolase, a muconolactone isomerase, a muconate cycloisomerase, a beta-ketoadipyl-CoA dehydrogenase, a 3-hydroxyadipyl-CoA dehydratase, a 2,3-dehydroadipyl-CoA transferase, a 2,3-dehydroadipyl-CoA hydrolase, a 2,3-dehydroadipyl-CoA ligase, a muconate reductase, a 2-maleylacetate reductase, a 2-maleylacetate dehydrogenase, a cis-3-hydroxy-4-hexendioate dehydratase, a 2-maleylacetate aminoatransferase, a 2-maleylacetate aminating oxidoreductase, a cis-3-amino-4-hexendioate deaminase, and a muconate cis/trans isomerase. Other muconate pathway enzymes also are provided. Additionally provided are methods of producing muconate.

  本发明提供了一种具有粘液酸盐途径的非天然微生物有机体，该有机体具有至少一种编码粘液酸盐途径酶的外源核酸，其表达量足以产生粘液酸盐。粘液酸盐途径包括一种酶，该酶选自以下组成的组 β-酮硫醇酶、β-酮基二烯丙基-CoA 水解酶、β-酮基二烯丙基-CoA 转移酶、β-酮基二烯丙基-CoA 连接酶、2-富马酸乙酸酯还原酶、2-富马酸乙酸酯脱氢酶、反式-3-羟基-4-己烯酸脱水酶、2-富马酸氨基转移酶、2-富马酸氨化氧化还原酶、反式-3-氨基-4-己烯酸脱氨酶、β-酮基己二酸烯醇-内酯水解酶、粘蛋白内酯异构酶、木糖醛酸环异构酶、β-酮基二烯丙基-CoA 脱氢酶、3-羟基二烯丙基-CoA 脱水酶、2,3-脱氢二烯丙基-CoA 转移酶、2,3-脱氢二烯丙基-CoA 水解酶、2,3-脱氢二烯丙基-CoA 连接酶、木糖醛酸还原酶、2-马来酰乙酸还原酶、2-马来酰乙酸脱氢酶、顺式-3-羟基-4-己二酸脱水酶、2-马来酰乙酸氨基转移酶、2-马来酰乙酸氨基氧化还原酶、顺式-3-氨基-4-己二酸脱氨酶和丙二酸顺式/反式异构酶。还提供了其他粘菌酸途径酶。此外，还提供了生产粘菌酸的方法。
• Microorganisms and processes for producing terephthalic acid and its salts
  申请人：Genomatica, Inc.

  公开号：US10059967B2

  公开（公告）日：2018-08-28

  The invention provides non-naturally occurring microbial organisms having a (2-hydroxy-3-methyl-4-oxobutoxy) phosphonate (2H3M40P) pathway, p-toluate pathway, and/or terephthalate pathway. The invention additionally provides methods of using such organisms to produce 2H3M40P, p-toluate or terephthalate. Also provided herein are processes for isolating bio-based aromatic carboxylic acid, in particular, p-toluic acid or terephthalic acid, from a culture medium, wherein the processes involve contacting the culture medium with sufficient carbon dioxide (CO2) to lower the pH of the culture medium to produce a precipitate comprised of the aromatic carboxylic acid.

  本发明提供了具有（2-羟基-3-甲基-4-氧代丁氧基）膦酸盐（2H3M40P）途径、对甲苯磺酸途径和/或对苯二甲酸盐途径的非天然微生物。本发明还提供了利用此类生物生产 2H3M40P、对甲苯磺酸酯或对苯二甲酸酯的方法。本发明还提供了从培养基中分离生物基芳香族羧酸（尤其是对甲苯甲酸或对苯二甲酸）的工艺，其中涉及将培养基与足够的二氧化碳（CO2）接触，以降低培养基的 pH 值，从而产生由芳香族羧酸组成的沉淀。