2-(N,N-dimethylaminocarbonyl)ethyldiphenylphosphane | 95713-62-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(N,N-dimethylaminocarbonyl)ethyldiphenylphosphane
• 英文别名: 3-(diphenylphosphanyl)-N,N-dimethylpropanamide；3-(diphenylphosphino)-N,N-dimethylpropionamide；N,N-dimethyl-3-diphenylphosphinopropionamide；3-diphenylphosphanyl-N,N-dimethylpropanamide
• CAS: 95713-62-5
• 化学式: C₁₇H₂₀NOP
• 分子量: 285.326
• InChiKey: RIIOUVIHNMXECB-UHFFFAOYSA-N

物化性质

• 沸点：
  413.7±28.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N,N-二甲基丙烯酰胺 、 (tert-butyldimethylsilyl)diphenylphosphine 在 四丁基氟化铵 、 水 作用下， 以 四氢呋喃 、 N,N-二甲基甲酰胺 为溶剂， 反应 0.25h， 以76%的产率得到2-(N,N-dimethylaminocarbonyl)ethyldiphenylphosphane
  参考文献：
  名称：

  Fluoride-mediated phosphination of alkenes and alkynes by silylphosphines

  摘要：

  Regioselective phosphination of carbon-carbon unsaturated bonds by a fluoride-mediated reaction of silylphosphines is described. Alkenes and alkynes having a directing group, such as an aromatic or a carbonyl group, reacted to form a carbon-phosphorus bond under mild conditions. When an anhydrous fluoride source was applied in the presence of an electrophile, the corresponding three-component coupling product was obtained. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2004.10.098

文献信息

• Catalyst- and solvent-free hydrophosphination and multicomponent hydrothiophosphination of alkenes and alkynes
  作者：Yanina Moglie、María José González-Soria、Iris Martín-García、Gabriel Radivoy、Francisco Alonso

  DOI：10.1039/c6gc00903d

  日期：——

  The hydrophosphination of carbon-carbon multiple bonds has been generally performed under acid, base or metal catalysis in different solvents. Herein, alkyl and alkenyl tertiary phosphines are obtained by the addition...

  碳-碳多键的氢磷酸化通常已经在不同溶剂中的酸，碱或金属催化下进行。在本文中，通过加成获得烷基和烯基叔膦。
• Catalyst-free hydrophosphination of alkenes in presence of 2-methyltetrahydrofuran: a green and easy access to a wide range of tertiary phosphines
  作者：Damien Bissessar、Julien Egly、Thierry Achard、Pascal Steffanut、Stéphane Bellemin-Laponnaz

  DOI：10.1039/c9ra04896k

  日期：——

  reaction that is free of base, acid and catalyst, using only 2-methyltetrahydrofuran as additive has been performed. A new family of mono-, di-, tri- and tetra-phosphines compounds are obtained in good to excellent yields by adding diphenylphosphine to alkenes, mono- and polyfunctional acrylics (based on acrylate and methacrylate motifs) and acrylamide substrates. Addition of four equivalent of bio-mass

  已经进行了不含碱、酸和催化剂的氢膦化反应，仅使用 2-甲基四氢呋喃作为添加剂。通过将二苯基膦添加到烯烃、单官能和多官能丙烯酸树脂（基于丙烯酸酯和甲基丙烯酸酯基体）和丙烯酰胺基材中，可以以良好至优异的产率获得一系列新的单、二、三和四膦化合物。将四当量的生物质衍生的 2-MeTHF 添加到反应介质中可以提高转化率和反应时间，并降低反应物对氧化的敏感性。这种简单、直接和原子经济的方法尊重绿色化学的原则。此外，在每种情况下，这种转化都显示出对反马尔科夫尼科夫产物的专有区域选择性。
• Process for the production of glycol aldehyde and catalyst therefor
  申请人：THE HALCON SD GROUP, INC.

  公开号：EP0130085A1

  公开（公告）日：1985-01-02

  This invention discloses a process and accompanying catalyst for the preparation of glycol aldehyde from the reaction of formaldehyde, carbon monoxide and hydrogen in the presence of a rhodium phosphine amide catalyst having the formula: wherein M is a metal selected from the group of rhodium, cobalt, ruthenium and mixtures thereof. X is an anion selected from the class of halides, psuedohalides, hydrides, and deprotonated strong carboxylic acids; P is phosphorous; R1 is an aliphatic or aromatic group containing from 1-20 carbon atoms; R2 is an aliphatic or aromatic group containing from 0-20, carbon atoms and may further comprise oxygen, nitrogen and/or sulfur atoms which may also be directly bonded to the amide C(O)N carbon or nitrogen; R3 and R. are aliphatic or aromatic groups containing from 1-50 carbon atoms; x ranges from 0 to 3, y ranges from 1 to 5, and z from 1 to 4; the resultant compound further characterized by the absence of hydrogen on the amide nitrogen atom and the additional limitationthat if R2 is bonded to the amide nitrogen, then either R3 or R. is bonded to the amide carbon.

  本发明公开了一种由甲醛、一氧化碳和氢气在铑膦酰胺催化剂存在下反应制备乙二醇醛的工艺和配套催化剂，该催化剂具有以下式子： 其中 M 是选自铑、钴、钌及其混合物组的金属。 X 是选自卤化物、次卤化物、氢化物和去质子化强羧酸类的阴离子； P 是磷； R1 是含有 1-20 个碳原子的脂肪族或芳香族基团； R2 是脂肪族或芳香族基团，含 0-20 个碳原子，可进一步包括氧、氮和/或硫原子，这些原子也可直接键合到酰胺 C(O)N 碳或氮上； R3和R.是含1-50个碳原子的脂肪族或芳香族基团； x 为 0 至 3，y 为 1 至 5，z 为 1 至 4； 所得化合物的进一步特征是酰胺氮原子上不含氢，以及附加的限制条件：如果 R2 与酰胺氮键合，则 R3 或 R. 与酰胺碳键合。
• Process for the production of ethylene glycol
  申请人：Montvale Process Company Incorporated

  公开号：EP0158517A2

  公开（公告）日：1985-10-16

  A process for the preparation and purification of a glycol aldehyde intermediate which is later hydrogenated to ethylene glycol is disclosed. The process proceeds via the catalytic reaction of formaldehyde, carbon monoxide and hydrogen and utilizes a novel class of lipophilic rhodium phosphine amide catalysts and an effective solvent mixture, which enables efficient catalyst separation and recycle without the loss of a substantial amount of the expensive catalyst.

  本发明公开了一种制备和提纯乙二醇醛中间体的工艺，该中间体随后可氢化为乙二醇。 该工艺通过甲醛、一氧化碳和氢气的催化反应进行，并利用了一类新型亲脂性铑膦酰胺催化剂和一种有效的混合溶剂，从而实现了催化剂的高效分离和循环利用，且不会损失大量昂贵的催化剂。
• Novel catalyst compositions and process for olefin/CO copolymerization
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0259914A1

  公开（公告）日：1988-03-16

  Novel catalyst compositions, characterized in that they are based upon a) a palladium compound, b) an anion of an acid with a pKa of less than 2, with the proviso that the acid is not a hydrohalogenic acid, and c) a compound in which there occur one phosphorus atom and one or more nitrogen atoms which atoms bear no hydrogen, and in which compound each one of the nitrogen atoms is connected to the phosphorus atom by an organic bridging group which contains at least one carbon atom in the bridge.

  新型催化剂组合物，其特征在于它们基于 a) 钯化合物 b) 一种 pKa 小于 2 的酸的阴离子，但该酸不是氢卤酸，以及 c) 一种化合物，其中有一个磷原子和一个或多个氮原子，氮原子中不含氢原子，该化合物中的每个氮原子都通过一个有机桥基与磷原子相连，该桥基中至少含有一个碳原子。