镨(3+)油酸酯 | 88927-56-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 镨(3+)油酸酯
• 英文名称: N(6)-(2,3-Dihydroxypropyl)lysine
• 英文别名: (2S)-2-amino-6-(2,3-dihydroxypropylamino)hexanoic acid
• CAS: 88927-56-4
• 化学式: C₉H₂₀N₂O₄
• 分子量: 220.27
• InChiKey: YACLTUWSWMFZMM-MQWKRIRWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4
• 重原子数：
  15
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  116
• 氢给体数：
  5
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  镨(3+)油酸酯 、 苯基硫代氨基甲酰氯 生成 (2S)-6-[2,3-dihydroxypropyl(phenylcarbamothioyl)amino]-2-(phenylcarbamothioylamino)hexanoic acid
  参考文献：
  名称：

  LILOVA, ANTOANETTA;KLEINSCHMIDT, TRAUTE;NEDKOV, PETER;BRAUNITZER, GERHARD, BIOL. CHEM. HOPPE-SEYLER, 368,(1987) N 11, 1489-1493

  摘要：

  DOI：
• 作为产物：
  描述：

  N-alpha-叔丁氧羰基-L-赖氨酸 、 DL-甘油醛 以50%的产率得到
  参考文献：
  名称：

  LILOVA, ANTOANETTA;KLEINSCHMIDT, TRAUTE;NEDKOV, PETER;BRAUNITZER, GERHARD, BIOL. CHEM. HOPPE-SEYLER, 368,(1987) N 11, 1489-1493

  摘要：

  DOI：

文献信息

• N-N-ACYLOXYPROPYL LYSINE METHYL ESTER- AND N,N-BIS(N- ACYLOXYPROPYL)LYSINE METHYL ESTER-TYPE COMPOUNDS AND USE THEREOF AS SURFACE-ACTIVE AGENTS WITH AN ANTIMICROBIAL ACTIVITY
  申请人：Consejo Superior de Investigaciones Cientificas

  公开号：EP1813600A1

  公开（公告）日：2007-08-01

  The invention relates to novel compounds having an amphiphilic character (cationic, anionic, amphoteric and non-ionic), derivatives of n acyloxypropyl-type lysine amino acid according to general formula (I), which are intended to be used in the food, pharmaceutical and cosmetic industries as surface-active agents having a self-aggregating capacity and antimicrobial properties. Variations in activity are a function of the ionic nature of the final molecule, the number of fatty chains and the length thereof. The aforementioned products are prepared using a chemical synthesis method. The intermediate and final products are purified by means of liquid/liquid and liquid/solid extractions, crystallisations, cationic exchange chromatography and normal phase chromatography.

  本发明涉及具有两亲性（阳离子、阴离子、两性离子和非离子）的新型化合物，即根据通式（I）的酰氧基丙基型赖氨酸氨基酸的衍生物，其目的是在食品、制药和化妆品行业中用作具有自聚集能力和抗菌特性的表面活性剂。活性的变化取决于最终分子的离子性质、脂肪链的数量及其长度。上述产品采用化学合成方法制备。中间产物和最终产物通过液/液、液/固萃取、结晶、阳离子交换色谱法和正相色谱法进行纯化。
• N-N-Acyloxypropyl Lysine Methyl Ester-and N,N-Bis(N-Acyloxypropyl) Lysine Methyl Ester-Type Compounds and Use Thereof as Surface-Active Agents with an Antimicrobial Activity
  申请人：Perez Munoz Lourdes

  公开号：US20090203781A1

  公开（公告）日：2009-08-13

  The invention relates to novel compounds having an amphiphilic character (cationic, anionic, amphoteric and non-ionic), derivatives of n acyloxypropyl-type lysine amino acid according to general formula (I), which are intended to be used in the food, pharmaceutical and cosmetic industries as surface-active agents having a self-aggregating capacity and antimicrobial properties. Variations in activity are a function of the ionic nature of the final molecule, the number of fatty chains and the length thereof. The aforementioned products are prepared using a chemical synthesis method. The intermediate and final products are purified by means of liquid/liquid and liquid/solid extractions, crystallisations, cationic exchange chromatography and normal phase chromatography.