8-(3-aminoisoquinolin-1-yl)-6H-thiazolo[5,4-e]indol-7-ol | 872174-44-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 8-(3-aminoisoquinolin-1-yl)-6H-thiazolo[5,4-e]indol-7-ol
• 英文别名: 8-(3-aminoisoquinolin-1-yl)-6H-pyrrolo[2,3-g][1,3]benzothiazol-7-ol
• CAS: 872174-44-2
• 化学式: C₁₈H₁₂N₄OS
• 分子量: 332.385
• InChiKey: YKLRBIFUJPCGHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  116
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• KINASE INHIBITORS
  申请人：Takeda San Diego, Inc.

  公开号：EP1773807A2

  公开（公告）日：2007-04-18
• Kinase Inhibitors
  申请人：Bressi Jerome C.

  公开号：US20080153869A1

  公开（公告）日：2008-06-26

  The invention relates to compounds having one of the below formulae that may be used to inhibit kinases as well as compositions of matter and kits comprising these compounds, and methods using the compounds.
• [EN] KINASE INHIBITORS<br/>[FR] INHIBITEURS DE KINASE
  申请人：TAKEDA SAN DIEGO INC

  公开号：WO2005123672A2

  公开（公告）日：2005-12-29

  The invention relates to compounds having one of the below formulae that may be used to inhibit kinases as well as compositions of matter and kits comprising these compounds, and methodsusing the compounds.