(4S,5R)-6-(benzylamino)-4,5-bis(benzyloxy)-1-methoxy-1,6-dioxohexan-3-yl benzoate | 1354635-16-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4S,5R)-6-(benzylamino)-4,5-bis(benzyloxy)-1-methoxy-1,6-dioxohexan-3-yl benzoate
• CAS: 1354635-16-7
• 化学式: C₃₅H₃₅NO₇
• 分子量: 581.665
• InChiKey: RVPXIVAHGNYMRU-ITBZIINNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.26
• 重原子数：
  43.0
• 可旋转键数：
  15.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  100.16
• 氢给体数：
  1.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  (4S,5R)-6-(benzylamino)-4,5-bis(benzyloxy)-1-methoxy-1,6-dioxohexan-3-yl benzoate 在 甲醇 、 potassium carbonate 作用下， 生成
  参考文献：
  名称：

  Synthesis of novel mucic acid 1,4-lactone methyl ester 3-O-ferulate related to an extractive component isolated from the peels of Citrus sudachi

  摘要：

  Synthesis of a new type of mucic acid 1,4-lactone methyl ester 3-O-ferulate related to an extractive component isolated from Citrus sudachi, and its diastereomer has been achieved by employing stereodivergent dihydroxylation as a key step. The structures of the final products are fully characterized by spectroscopic methods and compared with that of the natural product. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.11.066
• 作为产物：
  描述：

  在 4-二甲氨基吡啶 、 sodium tetrahydroborate 、 sodium periodate 、 四氧化锇 、 溴 、 N-甲基吗啉氧化物 、 三乙胺 作用下， 以 四氢呋喃 、 甲醇 、 二氯甲烷 、 水 、 丙酮 为溶剂， 生成 (4S,5R)-6-(benzylamino)-4,5-bis(benzyloxy)-1-methoxy-1,6-dioxohexan-3-yl benzoate
  参考文献：
  名称：

  Synthesis of novel mucic acid 1,4-lactone methyl ester 3-O-ferulate related to an extractive component isolated from the peels of Citrus sudachi

  摘要：

  Synthesis of a new type of mucic acid 1,4-lactone methyl ester 3-O-ferulate related to an extractive component isolated from Citrus sudachi, and its diastereomer has been achieved by employing stereodivergent dihydroxylation as a key step. The structures of the final products are fully characterized by spectroscopic methods and compared with that of the natural product. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.11.066