Norepinephrine d-bitartrate | 69815-49-2

• 物质功能分类: 生物化工 - 提取物 - 植物提取物
• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: Norepinephrine d-bitartrate
• 英文别名: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol;2,3-dihydroxybutanedioic acid;hydrate
• CAS: 69815-49-2
• 化学式: C12H19NO10
• 分子量: 337.28
• InChiKey: LNBCGLZYLJMGKP-JZGIKJSDSA-N

物化性质

• 熔点：
  102-105 °C
• 比旋光度：
  -46 º (c=0.5, HCl)
• 溶解度：
  在水中的溶解度50 mg/mL，澄清

计算性质

• 辛醇/水分配系数(LogP)：
  -2.86
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  203
• 氢给体数：
  9
• 氢受体数：
  11

安全信息

• 安全说明：
  S45
• 危险类别码：
  R26/27/28
• WGK Germany：
  3
• 海关编码：
  2922210000

制备方法与用途

用途 

肾上腺素受体激素药。

文献信息

• PACKAGED, SEALED CONTAINER SYSTEM FOR STABLE STORAGE OF AN OXYGEN SENSITIVE PHARMACEUTICAL FORMULATION
  申请人：BAXTER INTERNATIONAL INC.

  公开号：US20210275470A1

  公开（公告）日：2021-09-09

  A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.
• [EN] PACKAGED, SEALED CONTAINER SYSTEM FOR STABLE STORAGE OF AN OXYGEN SENSITIVE PHARMACEUTICAL FORMULATION<br/>[FR] SYSTÈME DE RÉCIPIENT SCELLÉ CONDITIONNÉ DE STOCKAGE STABLE DE FORMULATION PHARMACEUTIQUE SENSIBLE À L'OXYGÈNE
  申请人：BAXTER INT

  公开号：WO2021178946A1

  公开（公告）日：2021-09-10

  A packaged, sealed container system for stable storage of a formulation of an oxygen-sensitive pharmaceutical compound, the packaged, sealed container system comprising a primary container including therein a formulation of an oxygen-sensitive pharmaceutical compound, a secondary outer container comprising a first flexible sheet layer, an opposing second flexible sheet layer, and a seal disposed along a common peripheral edge of the first and second flexible sheet layers, such that the primary container is disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. An oxygen scavenger is also disposed between and enclosed by the first and second flexible sheet layers of the secondary outer container. The oxygen scavenger is in fluid communication with the contents of the primary container.