1,1'-((2,5-bis((trimethylsilyl)ethynyl)-1,4-phenylene)bis(oxy))bis(13,13-diisopropyl-14-methyl-3,6,9-trioxa-13-silapentadec-11-yne) | 1030599-43-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1,1'-((2,5-bis((trimethylsilyl)ethynyl)-1,4-phenylene)bis(oxy))bis(13,13-diisopropyl-14-methyl-3,6,9-trioxa-13-silapentadec-11-yne)
• CAS: 1030599-43-9
• 化学式: C₅₂H₉₀O₈Si₄
• 分子量: 955.624
• InChiKey: KUTLDNHUPPGUCO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.44
• 重原子数：
  64.0
• 可旋转键数：
  28.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  73.84
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  1,1'-((2,5-bis((trimethylsilyl)ethynyl)-1,4-phenylene)bis(oxy))bis(13,13-diisopropyl-14-methyl-3,6,9-trioxa-13-silapentadec-11-yne) 在 乙醇 、 potassium carbonate 作用下， 以95.6%的产率得到3-[2-[2-[2-[2,5-Diethynyl-4-[2-[2-[2-[3-tri(propan-2-yl)silylprop-2-ynoxy]ethoxy]ethoxy]ethoxy]phenoxy]ethoxy]ethoxy]ethoxy]prop-1-ynyl-tri(propan-2-yl)silane
  参考文献：
  名称：

  Fluorescence Self-Quenching of a Mannosylated Poly(p-phenyleneethynylene) Induced by Concanavalin A

  摘要：

  We report that static quenching of a mannosylated conjugated polymer (sugar-PPE) by Concanavalin A is positively dependent upon sugar-PPE concentration, that is, the recorded Stern-Volmer constants increase with increasing sugar-PPE concentration. Comparison with data obtained from isothermal titration calorimetry (ITC) display the increased sensitivity of the quenching method when compared to ITC. The proposed mechanism suggests the interaction of two or more chains of PPE with one Con A molecule leading to a quenched sugar-PPE-Con A construct.

  DOI：

  10.1021/ja802094s
• 作为产物：
  描述：

  3-[2-[2-[2-[2,5-Diiodo-4-[2-[2-[2-[3-tri(propan-2-yl)silylprop-2-ynoxy]ethoxy]ethoxy]ethoxy]phenoxy]ethoxy]ethoxy]ethoxy]prop-1-ynyl-tri(propan-2-yl)silane 、 三甲基乙炔基硅 在 bis-triphenylphosphine-palladium(II) chloride 哌啶 、 copper(l) iodide 作用下， 以 四氢呋喃 为溶剂， 以61.5%的产率得到1,1'-((2,5-bis((trimethylsilyl)ethynyl)-1,4-phenylene)bis(oxy))bis(13,13-diisopropyl-14-methyl-3,6,9-trioxa-13-silapentadec-11-yne)
  参考文献：
  名称：

  Fluorescence Self-Quenching of a Mannosylated Poly(p-phenyleneethynylene) Induced by Concanavalin A

  摘要：

  We report that static quenching of a mannosylated conjugated polymer (sugar-PPE) by Concanavalin A is positively dependent upon sugar-PPE concentration, that is, the recorded Stern-Volmer constants increase with increasing sugar-PPE concentration. Comparison with data obtained from isothermal titration calorimetry (ITC) display the increased sensitivity of the quenching method when compared to ITC. The proposed mechanism suggests the interaction of two or more chains of PPE with one Con A molecule leading to a quenched sugar-PPE-Con A construct.

  DOI：

  10.1021/ja802094s