1-C6H5CONHCH2-1,2-dicarba-closo-dodecaborane(12) | 224790-08-3

• 英文名称: 1-C6H5CONHCH2-1,2-dicarba-closo-dodecaborane(12)
• CAS: 224790-08-3
• 化学式: C₁₀H₁₉B₁₀NO
• 分子量: 277.377
• InChiKey: JGTVHOOTDQPLRI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  1-NH2CH2-1,2-closo-C2B10H11 、 苯甲酸 、 N,N'-羰基二咪唑 在 吡啶 作用下， 以 四氢呋喃 、 吡啶 为溶剂， 以76%的产率得到1-C6H5CONHCH2-1,2-dicarba-closo-dodecaborane(12)
  参考文献：
  名称：

  Coupling of Amino Carboranes to Carboxylic Acid Containing Substrates

  摘要：

  The reactivity of the known amino carboranes 1-H2NCH2-1,2-C2B10H11 and 7-H3N-7-CB10H12 With carboxylic acid containing substrates was investigated. The reactions studied using the coupling reagent, 1,1'-carbonyldiimidazole, resulted in the preparation of a series of amides in moderate to high yield. The relative importance of this type of research resides in the fact that it allows the introduction of amino acids in close contact with the carborane cage. These compounds can constitute a new generation of substrates useful in boron neutron capture therapy. Our emphasis lies in the development of suitable synthetic schemes allowing the preparation of this type of compound. Experimental details and analytical data supporting the formulation of the prepared compounds are reported.

  DOI：

  10.1021/ic981223h

文献信息

• Synthesis and new application of green and recyclable cyclic poly(<scp>L</scp> -lactide)-clay hybrid
  作者：Aitha Vishwa Prasad、Algin Oh Biying、Woo Yuan Ling、Ludger Paul Stubbs、Yinghuai Zhu

  DOI：10.1002/pola.26829

  日期：2013.10

  PLLAs were used to stabilize palladium nanoparticles synthesized by a wet chemical method. It was found that the palladium particles were smaller with cyclic PLLA stabilizer (∼5–10 nm) than the particles obtained from linear PLLA. The cyclic PLLA‐clay hybrid was prepared by a zwitterionic ring‐opening polymerization catalyzed by in situ‐generated N‐heterocyclic carbene catalyst. Palladium (0) nanoparticles

  我们报告了可生物降解的环状聚（L-丙交酯）（PLLA）作为新型稳定剂的应用；环状PLLA粘土杂化材料的合成与应用作为可循环使用的催化剂载体。环状PLLA用于稳定通过湿化学法合成的钯纳米粒子。结果发现，使用环状PLLA稳定剂（〜5-10 nm）的钯粒子比线性PLLA所得的钯粒子小。通过原位催化的两性离子开环聚合反应制备环状PLLA-粘土杂化体生成的N杂环卡宾催化剂。钯（0）纳米颗粒被支撑并很好地分散在环状PLLA-粘土杂化体上，形成了一种新的纳米复合材料。发现该纳米复合材料是芳基卤化物与各种胺的氨基羰基化反应的高效且可回收的催化剂。©2013 Wiley Periodicals，Inc. J. Polym。科学，A部分：Polym。化学 2013，51，4167-4174
• Synthesis of carboranyl amides catalyzed by recyclable Pd (0) nanoparticles supported on carbon nanotubes (CNTs)
  作者：Algin Oh Biying、Karen Tang Yuanting、Narayan S. Hosmane、Zhu Yinghuai

  DOI：10.1016/j.jorganchem.2013.05.014

  日期：2013.12

  Palladium (0) nanoparticles with small size and narrow size distribution were synthesized conveniently and supported on CNTs. The supported nano-Pd-0 was found to be a highly efficient and recyclable catalyst for the aminocarboranylation reaction of aryl halide. Thus, a series of carboranyl amides, 1-R-2-[ CH2NHC(=O)Ar]-1,2-C2B10H10 (R = H, Me; Ar = C6H5, 4-Me-C6H5, 4-MeO-C6H5 and 2-C5NH4), were synthesized and fully characterized. The catalyst was recyclable at least three times with sustained activity. (C) 2013 Elsevier B.V. All rights reserved.