butyl 5-oxopentanoate | 90647-18-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: butyl 5-oxopentanoate
• 英文别名: 4-Formyl-buttersaeure-butylester
• CAS: 90647-18-0
• 化学式: C₉H₁₆O₃
• 分子量: 172.224
• InChiKey: ZBERHGOYDITCGF-UHFFFAOYSA-N

物化性质

• 沸点：
  73-74 °C(Press: 0.3 Torr)
• 密度：
  0.968±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  butyl 5-oxopentanoate 在 triethylamine tris(hydrogen fluoride) 、 N,N-二乙基-alpha,alpha-二氟-3-甲基苄胺 作用下， 反应 0.33h， 以60%的产率得到butyl 5,5-difluoropentanoate
  参考文献：
  名称：

  Synthesis of gem-difluorides from aldehydes using DFMBA

  摘要：

  Synthesis of gem-difluorides from aldehydes was effectively achieved using DFMBA and Et3N-3HF under microwave irradiation or conventional thermal heating. Both aromatic and aliphatic aldehydes could be converted to the corresponding gem-difluorides in good yields. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2005.02.004
• 作为产物：
  描述：

  butyl 5-hydroxypentanoate 在 pyridinium chlorochromate 作用下， 生成 butyl 5-oxopentanoate
  参考文献：
  名称：

  Synthesis of gem-difluorides from aldehydes using DFMBA

  摘要：

  Synthesis of gem-difluorides from aldehydes was effectively achieved using DFMBA and Et3N-3HF under microwave irradiation or conventional thermal heating. Both aromatic and aliphatic aldehydes could be converted to the corresponding gem-difluorides in good yields. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jfluchem.2005.02.004

文献信息

• [EN] C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS<br/>[FR] COMPOSÉS DE TÉTRACYCLINE C7-FLUOROSUBSTITUÉE
  申请人：TETRAPHASE PHARMACEUTICALS INC

  公开号：WO2010017470A1

  公开（公告）日：2010-02-11

  The present invention is directed to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (A) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (A) and its therapeutic use.

  本发明涉及一种由结构式（A）表示的化合物，或其药学上可接受的盐。结构式（A）的变量在此处定义。还描述了包括结构式（A）化合物的药物组合物及其治疗用途。
• POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF
  申请人：Glinka Tomasz

  公开号：US20100152098A1

  公开（公告）日：2010-06-17

  Disclosed are compounds having polybasic functionalities. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.

  本发明涉及具有多元功能的化合物。这些化合物可以抑制细菌外排泵抑制剂，并与抗菌剂结合使用，以治疗或预防细菌感染。这些组合物可以有效地对抗通过外排泵机制对抗菌剂产生抗性的细菌感染。
• Photographic elements comprising antistatic layers
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0704755A1

  公开（公告）日：1996-04-03

  Light-sensitive photographic element comprising a polymeric film base, a silver halide emulsion layer, and an antistatic layer comprising a low viscosity and highly sulfonated water soluble polyacetal (preferably obtained by reaction of a low viscosity polyvinyl alcohol and a sulfonated aldehyde), a hydrophobic binder selected from the group consisting of a water dispersible sulfopolyester and a latex polymer having hydrophilic functionality, and a polyfunctional aldehyde crosslinking agent. The antistatic layer may be present as a backing layer on the side of the base opposite the silver halide emulsion layer, as a subbing layer between the base and the emulsion layer in a single or double side coated photographic element, and/or as a subbing layer between the base and a different backing layer.

  感光照相元件，包括聚合物膜基、卤化银乳剂层和抗静电层，抗静电层包括低粘度和高磺化的水溶性聚缩醛（最好是由低粘度聚乙烯醇和磺化醛反应得到）、从水分散性聚硫酯和具有亲水功能的乳胶聚合物组成的组中选出的疏水粘合剂以及多官能醛交联剂。抗静电层可以作为底座上与卤化银乳剂层相对的一面的背衬层，也可以作为单面或双面涂层感光元件中底座与乳剂层之间的辅助层，和/或作为底座与不同背衬层之间的辅助层。
• Anti-corrosion additives
  申请人：The Lubrizol Corporation

  公开号：US10119091B2

  公开（公告）日：2018-11-06

  A lubricant composition comprising an oil of lubricating viscosity and an N-hydrocarbyl-substituted aminoester, wherein the N-hydrocarbyl substituent comprises a hydrocarbyl group of at least 3 carbons atoms, with a branch at the 1 or 2 position of the hydrocarbyl chain, provides good iron and copper corrosion performance in driveline or gear applications.

  一种润滑剂组合物由具有润滑粘度的油和一种 N-烃基取代的氨基酯组成，其中 N-烃基取代基包括一个至少有 3 个碳原子的烃基，烃基链的 1 或 2 位有一个分支，这种组合物在传动系统或齿轮应用中具有良好的铁和铜腐蚀性能。
• Basic ashless additives
  申请人：The Lubrizol Corporation

  公开号：US10144897B2

  公开（公告）日：2018-12-04

  A lubricant composition comprising an oil of lubricating viscosity and an N-hydrocarbyl-substituted δ-aminoester or δ-aminothioester provides exhibits basicity and good seal performance. In certain embodiments the N-hydrocarbyl substituent comprises a hydrocarbyl group of at least 3 carbons atoms, with a branch at the 1 or 2 position of the hydrocarbyl chain.

  一种润滑剂组合物由具有润滑粘度的油和δ-氨基酯或δ-硫代氨基酯的N-烃基取代基组成，具有碱性和良好的密封性能。在某些实施方案中，N-烃基取代基包括一个至少有 3 个碳原子的烃基，烃基链的 1 位或 2 位有一个分支。