4,8-dihydroxy-1-[3-(N-tertiarybutoxycarbonylglycyloxy)propyl-amino]-anthracene-9,10-dione | 252683-49-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 4,8-dihydroxy-1-[3-(N-tertiarybutoxycarbonylglycyloxy)propyl-amino]-anthracene-9,10-dione
• 英文别名: 3-[(4,8-Dihydroxy-9,10-dioxoanthracen-1-yl)amino]propyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate
• CAS: 252683-49-1
• 化学式: C₂₄H₂₆N₂O₈
• 分子量: 470.479
• InChiKey: KJHCQFJKYNNOJP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  34
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  151
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS
  申请人：BTG INTERNATIONAL LIMITED

  公开号：EP1087935B1

  公开（公告）日：2004-08-18
• 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION
  申请人：Pharmacia Corporation

  公开号：EP1296971A2

  公开（公告）日：2003-04-02
• [EN] 2-FLUOROBENZENESULFONYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION<br/>[FR] COMPOSES DE 2-FLUOROBENZENESULFONYLE UTILISES POUR LE TRAITEMENT D'INFLAMMATIONS
  申请人：PHARMACIA CORP

  公开号：WO2001081332A2

  公开（公告）日：2001-11-01

  Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more 2-fluorobenzenesulfonyl compounds corresponding to Formula (I) wherein A, R?1, R2, and R3¿ are as described in the specification, and novel 2-fluorobenzenesulfonyl compounds within Formula (I).