4-(4-methoxyphenyl)pyridine-2,6-dicarbaldehyde | 1620511-30-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-(4-methoxyphenyl)pyridine-2,6-dicarbaldehyde
• CAS: 1620511-30-9
• 化学式: C₁₄H₁₁NO₃
• 分子量: 241.246
• InChiKey: IYWBCUMWXMYVJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  56.3
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  isonitrosoacetophenone hydrazone 、 4-(4-methoxyphenyl)pyridine-2,6-dicarbaldehyde 在 溶剂黄146 作用下， 以 乙醇 为溶剂， 反应 12.0h， 以45%的产率得到4-(4-methoxyphenyl)-2,6-bis(6-phenyl-1,2,4-triazin-3-yl)pyridine
  参考文献：
  名称：

  An efficient synthetic approach to 4′,5,5″-triaryl-2,2′:6′,2″-terpyridines

  摘要：

  An efficient synthetic approach is proposed to construct 4',5,5 ''-triaryl-2,2':6',2 ''-terpyridines using two methods of pyridine ring construction, that is, the Weiss method and the '1,2,4-triazine' methodology. Due to the use of '1,2,4-triazine' methodology in the last step, aza-analogues of terpyridines as well as cycloalkane-annulated terpyridines have been synthesized which are inaccessible by other reported methods. The presented approach involves the use of readily available reagents and simple procedures. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2015.12.006
• 作为产物：
  描述：

  (E)-1-(furan-2-yl)-3-(4-methoxyphenyl)prop-2-en-1-one 在 manganese(IV) oxide 、 sodium tetrahydroborate 、 potassium permanganate 、 氯化亚砜 、 盐酸羟胺 、 sodium hydroxide 作用下， 以 吡啶 、 甲醇 、 乙醇 、 水 、 1,2-二氯乙烷 、 仲丁醇 为溶剂， 反应 90.41h， 生成 4-(4-methoxyphenyl)pyridine-2,6-dicarbaldehyde
  参考文献：
  名称：

  An efficient synthetic approach to 4′,5,5″-triaryl-2,2′:6′,2″-terpyridines

  摘要：

  An efficient synthetic approach is proposed to construct 4',5,5 ''-triaryl-2,2':6',2 ''-terpyridines using two methods of pyridine ring construction, that is, the Weiss method and the '1,2,4-triazine' methodology. Due to the use of '1,2,4-triazine' methodology in the last step, aza-analogues of terpyridines as well as cycloalkane-annulated terpyridines have been synthesized which are inaccessible by other reported methods. The presented approach involves the use of readily available reagents and simple procedures. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2015.12.006

文献信息

• Formation of a hetero[3]rotaxane by a dynamic component-swapping strategy
  作者：Eleanor A. Wilson、Nicolaas A. Vermeulen、Paul R. McGonigal、Alyssa-Jennifer Avestro、Amy A. Sarjeant、Charlotte L. Stern、J. Fraser Stoddart

  DOI：10.1039/c4cc03612c

  日期：——

  the mechanically interlocked components between two different homo[3]rotaxanes, constituted of dumbbells containing two secondary dialkylammonium ion recognition sites encircled by two [24]crown-8 rings, each containing a couple of imine bonds, affords a statistical mixture of a hetero[3]rotaxane along with the two homo[3]rotaxanes, indicating that neither selectivity nor cooperativity is operating

  两种不同的同[3]轮烷之间的机械互锁组分的酸催化加扰，该哑铃由包含两个被两个[24]冠-8环环绕的仲二烷基二烷基铵离子识别位的哑铃组成，每个环都含有一对亚胺键，从而提供了统计数据杂[3]轮烷与两种均[3]轮烷的混合物，表明在组装过程中选择性和协同性都没有作用。