4-噻唑烷羧酸,3-乙酰基-,(-)- | 27379-58-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 4-噻唑烷羧酸,3-乙酰基-,(-)-
• 英文名称: D-Glucitol monomyristate
• 英文别名: [(2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl] tetradecanoate
• CAS: 27379-58-4
• 化学式: C₂₀H₄₀O₇
• 分子量: 392.533
• InChiKey: QNOBYPFIKDXBPL-PIKOESSRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  27
• 可旋转键数：
  19
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  127
• 氢给体数：
  5
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  山梨醇 、 肉豆蔻酸 在 lipase Candida sp. 99–125 作用下， 以 水 、 叔丁醇 为溶剂， 生成 4-噻唑烷羧酸,3-乙酰基-,(-)- 、 [(2R,3R,4R,5S)-2,3,4,5,6-pentahydroxyhexyl] tetradecanoate
  参考文献：
  名称：

  Enzymatic production and functional characterization of d-sorbitol monoesters with various fatty acids

  摘要：

  Sugar fatty acid esters are surfactants that are widely used in food, cosmetics, and pharmaceutical industries. In this study, enzymatic production of o-sorbitol monoesters with various fatty acids (C10-C18) was assessed. Reactions were performed in tert-butanol at 40 degrees C, catalyzed by Candida sp. 99-125 lipase. Dissolution of the substrates was found to be the limiting step of the reaction, and hence preheating was performed to increase the solubility of D-sorbitol. Thus, the yield of D-sorbitol palmitate was increased from 734 to 31.6 mM. The results demonstrated that the specific lipase preferred long-chain fatty acids. The surface-active properties. of the products were also determined. (C) 2015 Published by Elsevier B.V.

  DOI：

  10.1016/j.catcom.2015.09.010

文献信息

• SURFACTANT COMPOSITION
  申请人：Imperial Chemical Industries Plc.

  公开号：EP1755545A1

  公开（公告）日：2007-02-28
• Surfactant Composition
  申请人：Bevinakatti Hanamanthsa S.

  公开号：US20090012185A1

  公开（公告）日：2009-01-08

  A surfactant composition contains at least one sorbitan ester and at least one sorbitol ester wherein the mean number of carbon atoms of the hydrophobe of the sorbitan ester is greater than that of the sorbitol ester. The surfactant composition is particularly suitable for use in stabilising emulsions, especially personal care or cosmetic products.
• US8673987B2
  申请人：——

  公开号：US8673987B2

  公开（公告）日：2014-03-18
• [EN] SURFACTANT COMPOSITION<br/>[FR] COMPOSITION DE TENSIOACTIF
  申请人：ICI PLC

  公开号：WO2005102265A1

  公开（公告）日：2005-11-03

  A surfactant composition contains at least one sorbitan ester and at least one sorbitol ester wherein the mean number of carbon atoms of the hydrophobe of the sorbitan ester is greater than that of the sorbitol ester. The surfactant composition is particularly suitable for use in stabilising emulsions, especially personal care or cosmetic products.