1-cyclopropyl-1-(4-methoxy-phenyl)-but-3-yn-1-ol | 92251-15-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-cyclopropyl-1-(4-methoxy-phenyl)-but-3-yn-1-ol
• 英文别名: 1-Cyclopropyl-1-(4-methoxy-phenyl)-but-3-in-1-ol
• CAS: 92251-15-5
• 化学式: C₁₄H₁₆O₂
• 分子量: 216.28
• InChiKey: QANGLPHTGJWXHR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.32
• 重原子数：
  16.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  29.46
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  苯甲醚 在 四氢呋喃 、 三氯化铝 、 amalgamated zinc 作用下， 生成 1-cyclopropyl-1-(4-methoxy-phenyl)-but-3-yn-1-ol
  参考文献：
  名称：

  The Prevalence of Daytime Napping and Its Relationship to Nighttime Sleep

  摘要：

  Many healthy adults report daytime napping. Surprisingly few studies, however have examined spontaneous napping behavior especially very short naps, in healthy adults. The authors examined the prevalence of power naps (lasting less than 20 minutes) and longer naps (20 minutes or more) and their effects on nighttime sleep in a group of healthy young and middle-aged adults. The young and middle-aged adults reported very similar sleep and napping patterns, with approximately 74% of the participants in both groups reporting they had napped during a 7-day sleep-log period. Almost half of the participants reported that the average nap lasted less than 20 minutes. A multivariant analysis of variance (MANOVA) found no significant differences between the no-nap and the power-nap or long-nap groups in sleep quantity or quality for either age group. The current data suggested that power napping occurs frequently in healthy adults and that spontaneous napping does not negatively affect nighttime sleep.

  DOI：

  10.1080/08964280109595773