4-异丙基烟醛 | 90732-15-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 4-异丙基烟醛
• 英文名称: 4-isopropyl-3-pyridinecarbaldehyde
• 英文别名: 4-i-propyl-3-pyridinecarboxylate；4-Isopropylnicotinaldehyde；4-propan-2-ylpyridine-3-carbaldehyde
• CAS: 90732-15-3
• 化学式: C₉H₁₁NO
• 分子量: 149.192
• InChiKey: PUQKHMLOCYESRV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  30
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N,N’-二羟基-2,3-二甲基-2,3-丁二胺 、 4-异丙基烟醛 以 甲醇 为溶剂， 以55 %的产率得到3-(1,3-dihydroxy-4,4,5,5-tetramethyl-imidazolidin-2-yl)-4-isopropylpyridine
  参考文献：
  名称：

  Relationship between phase transition temperature and accessible volume for substituent in Cu(hfac)2 chain-polymer complexes with pyridine-based nitroxides

  摘要：

  DOI：

  10.1016/j.poly.2022.116212
• 作为产物：
  描述：

  3-(1,3-dioxolan-2-yl)pyridine 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 、 copper(l) iodide 、 二甲基硫 、 草酸 作用下， 以 水 、 萘烷 为溶剂， 反应 4.42h， 生成 4-异丙基烟醛
  参考文献：
  名称：

  Comins, Daniel L.; Smith, Roy K.; Stroud, Eric D., Heterocycles, 1984, vol. 22, # 2, p. 339 - 344

  摘要：

  DOI：

文献信息

• Bi-functional complexes and methods for making and using such complexes
  申请人：Gouliaev Alex Haahr

  公开号：US11225655B2

  公开（公告）日：2022-01-18

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

  本发明涉及一种合成双功能复合物的方法，该复合物包括分子部分和识别分子部分的识别寡核苷酸部分。根据本发明的合成方法的一部分优选在一种或多种有机溶剂中进行，此时包含可选保护标签或寡核苷酸标识符的新生双功能复合物与固体支持物相连接，合成方法的另一部分优选在适合于将寡核苷酸标签酶加到溶液中的新生双功能复合物的条件下进行。
• Photoresponsive coordination of stilbazoles to metalloporphyrins
  作者：Yuki Iseki、Eishun Watanabe、Atsunori Mori、Shohei Inoue

  DOI：10.1021/ja00069a033

  日期：1993.8

  The coordination of stilbazole derivatives to metalloporphyrins was investigated. Among the stilbazoles examined, a stilbazole with a bulky group such as 4-phenyl-3-stilbazole (4) showed considerable difference between the trans and cis isomers in its ability to coordinate to aluminum and zinc porphyrins with bulky peripheral substituents. The extent of coordination of 4 to metalloporphyrins could be changed by the trans --> cis isomerization of 4 upon UV irradiation.
• COMINS, D. L.;SMITH, R. K.;STROUD, E. D., HETEROCYCLES, 1984, 22, N 2, 339-344
  作者：COMINS, D. L.、SMITH, R. K.、STROUD, E. D.

  DOI：——

  日期：——
• BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
  申请人：Nuevolution A/S

  公开号：EP2558577A1

  公开（公告）日：2013-02-20
• BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
  申请人：Gouliaev Alex Haahr

  公开号：US20130281324A1

  公开（公告）日：2013-10-24

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.