N-(2,4-Dimethyl-3-pentyl)-methansulfonamid | 60421-40-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N-(2,4-Dimethyl-3-pentyl)-methansulfonamid
• 英文别名: N-(2,4-dimethylpentan-3-yl)methanesulfonamide
• CAS: 60421-40-1
• 化学式: C₈H₁₉NO₂S
• 分子量: 193.31
• InChiKey: NASJJNYMVXVADO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N-(2,4-二甲基戊烷-3-亚基)羟胺 在 sodium hydroxide 、 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 生成 N-(2,4-Dimethyl-3-pentyl)-methansulfonamid
  参考文献：
  名称：

  Insertion of sulfonylnitrenes into the carbon-hydrogen bonds of saturated hydrocarbons. Acid-catalyzed thermolysis of N-alkyl sulfonamides

  摘要：

  DOI：

  10.1021/ja00430a043

文献信息

• Modulators of muscarinic receptors
  申请人：Makings R. Lewis

  公开号：US20080015179A1

  公开（公告）日：2008-01-17

  The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.

  本发明涉及肌胆碱受体调节剂。本发明还提供包含这种调节剂的组合物，并提供了用于治疗肌胆碱受体介导疾病的方法。
• COMPOUNDS USEFUL FOR TREATING NEURODEGENERATIVE DISORDERS
  申请人：Bronk Brian Scott

  公开号：US20110251379A1

  公开（公告）日：2011-10-13

  As described herein, the present invention provides compounds useful for treating or lessening the severity of a neurodegenerative disorder. The present invention also provides methods of treating or lessening the severity of such disorders wherein said method comprises administering to a patient a compound of the present invention, or composition thereof. Said method is useful for treating or lessening the severity of, for example, Alzheimer's disease.
• Compounds useful for treating neurodegenerative disorders
  申请人：Bronk Brian Scott

  公开号：US20130060013A1

  公开（公告）日：2013-03-07

  The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein each of the variables listed above are as defined and described herein, compositions thereof, and methods of using the same.
• US7858635B2
  申请人：——

  公开号：US7858635B2

  公开（公告）日：2010-12-28
• Insertion of sulfonylnitrenes into the carbon-hydrogen bonds of saturated hydrocarbons. Acid-catalyzed thermolysis of N-alkyl sulfonamides
  作者：David S. Breslow、Eleanor I. Edwards、Ernest C. Linsay、Hisanori Omura

  DOI：10.1021/ja00430a043

  日期：1976.7