4-异丙基苯酚钠 | 61260-32-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-异丙基苯酚钠
• 英文名称: sodium 4-isopropylbenzeneoxide
• 英文别名: sodium 4-isopropylyphenoxide；sodium p-cumyl phenolate；sodium p-isopropylphenolate；Phenol, 4-(1-methylethyl)-, sodium salt；sodium;4-propan-2-ylphenolate
• CAS: 61260-32-0
• 化学式: C₉H₁₁O*Na
• 分子量: 158.176
• InChiKey: VIJSNNRFTZHJFF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.11
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  23.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2907199090

反应信息

• 作为反应物：
  描述：

  4-异丙基苯酚钠 在 三氯化铝 、 copper dichloride 作用下， 以 吡啶 、 二硫化碳 为溶剂， 生成 4-(4-isopropylphenoxy)phenacyl chloride
  参考文献：
  名称：

  降血脂药的研究。I.3-苄基缩水甘油酸衍生物。

  摘要：

  3-苯甲酰基甘油酸衍生物被制备并测试了其在正常大鼠中的降脂性能。结构-活性关系研究表明，反式-3-(苯氧基苯甲酰基)-甘油酸具有降脂活性。在这些化合物中，反式-3-[4-(4-氯苯氧基)苯甲酰基]甘油酸（38）和反式-3-[4-(4-溴苯氧基)苯甲酰基]甘油酸（39）具有非常强的活性。

  DOI：

  10.1248/cpb.32.3066
• 作为产物：
  描述：

  4-异丙基苯酚 在 sodium methylate 作用下， 反应 0.17h， 生成 4-异丙基苯酚钠
  参考文献：
  名称：

  Ujvary; Kis Tamas; Varjas, Acta Chimica Hungarica, 1983, vol. 113, # 2, p. 165 - 175

  摘要：

  DOI：

文献信息

• Curable poly(aryloxyphosphazene) copolymers
  申请人：THE FIRESTONE TIRE & RUBBER COMPANY

  公开号：EP0215278A1

  公开（公告）日：1987-03-25

  Low or no chlorine content poly(aryloxyphosphazene) copolymers useful for fireproof foams are surprisingly produced in a one step process without use of excess phenoxide reactant over a shorter than conventional time period by (a) adding linear (NPCl2)n to a mixture of phenoxides comprising alkali or alkaline earth metal phenoxide, alkylphenoxide and allylphenoxide in quantities such that the total of the phenoxides is the equivalent of the total chlorine atoms in the (NPCl2)n and allylphenoxide is present in an amount equivalent to from about 2% to about 10% of the chlorine atoms in the (NPCl2)n; and (b) reacting the admixture formed in step (a) at a temperature ranging from about 280°F. to about 320°F. for a time period ranging from about 7 hours to about 10 hours.

  用于防火泡沫塑料的低氯或无氯含量聚芳基氧基磷苯共聚物，竟然可以在不使用过量过氧化苯醚反应物的情况下，在比常规时间更短的时间内，通过以下方法一步制得：(a)将线性(NPCl2)n加入到由碱金属或碱土金属氧化酚组成的氧化酚混合物中；(b)将线性(NPCl2)n加入到由碱金属或碱土金属氧化酚组成的氧化酚混合物中、烷基酚和烯丙基酚的混合物中，使苯氧物的总量相当于 (NPCl2)n 中氯原子的总量，而烯丙基酚的含量相当于 (NPCl2)n 中氯原子的约 2%至约 10%；(b) 将步骤(a)中形成的混合物在约 280°F.至约 320°F 的温度下反应约 7 小时至约 10 小时。
• van Hooidonk,C.; Ginjaar,L., Recueil des Travaux Chimiques des Pays-Bas, 1967, vol. 86, p. 449 - 457
  作者：van Hooidonk,C.、Ginjaar,L.

  DOI：——

  日期：——
• Carbon-13 nuclear magnetic resonance spectroscopy. Substituent-induced chemical shift effects on cyclopropyl carbons of 4-substituted cyclopropylbenzenes
  作者：Yoshiaki Kusuyama、Christina Dyllick-Brenzinger、John D. Roberts

  DOI：10.1002/mrc.1270130516

  日期：1980.5

  AbstractCarbon‐13 chemical shifts of the cyclopropyl carbons of eleven 4‐substituted cyclopropylbenzenes have been measured under conditions effectively corresponding to infinite dilution in DCCI3. The substituent‐induced chemical shifts (SCS) of both the α and β carbons of the cyclopropane ring were found to be downfield with electron‐attracting groups and upfield for electron‐donating groups. The trends for the β carbons correspond to those observed for the β carbons of 4‐substituted phenylethenes, while the trends of the α carbons are similar to those found for the α carbons of 4‐substituted isopropyl benzenes. The results for the β carbons can be rationalized by postulating a substantial contribution from a hyperconjugative resonance effect involving the σ system of the benzene ring (and its 4‐substituent) and the C‐α—Cβ bonds of the cyclopropane ring. The effects on the α carbons are in accord with a very reasonable smaller inductive polarization of the C‐αC‐β bonds than encountered for the carbons of corresponding ethenyl‐ or ethynylbenzenes.
• Amino(hetero)arylmethylation of Phenols with <i>N</i>-[α-Amino(hetero)arylmethyl]benzotriazoles
  作者：Alan R. Katritzky、Ashraf A. A. Abdel-Fattah、Dmytro O. Tymoshenko、Sergei A. Belyakov、Ion Ghiviriga、Peter J. Steel

  DOI：10.1021/jo9903609

  日期：1999.8.1

  N-[alpha-Amino(hetero)arylmethyl]benzotriazole derived from a variety of (hetero)aromatic aldehydes were reacted with sodium phenolates to afford amino(hetero)arylmethylated phenols in high yields.
• FR2323675
  申请人：——

  公开号：——

  公开（公告）日：——