4-戊烯-1-酮,1-(1-环己烯-1-基)-2-苯基- | 154954-81-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-戊烯-1-酮,1-(1-环己烯-1-基)-2-苯基-
• 英文名称: 1-(1-oxo-2-phenyl-4-pentenyl)-1-cyclohexene
• 英文别名: 1-(cyclohexen-1-yl)-2-phenylpent-4-en-1-one
• CAS: 154954-81-1
• 化学式: C₁₇H₂₀O
• 分子量: 240.345
• InChiKey: GFMUQYATZKCGSW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.42
• 重原子数：
  18.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  4-戊烯-1-酮,1-(1-环己烯-1-基)-2-苯基- 在 叔丁基过氧化氢 、 正丁基锂 、 bis(acetylacetonate)oxovanadium 作用下， 以 乙醚 、 正己烷 、 苯 为溶剂， 反应 16.0h， 生成 syn-1-(1,2-epoxycyclohexyl)-1-(1-phenylethynyl)-2-phenyl-4-penten-1-ol
  参考文献：
  名称：

  Efficient routes to cyclic 2,3-epoxyalcohols from cycloalkenyl ketones, via cycloalkenyl alcohols

  摘要：

  The minimising of torsional strain and non-bonding interactions is proposed as the explanation of high diastereoselectivity observed in the epoxidation of cycloalkenyl alcohols. reported for twenty three examples. The resulting 2,3-epoxyalcohols are key intermediates in the synthesis of tricyclic 1, 2-diols and beta-hydroxy ketones

  DOI：

  10.1016/s0040-4020(01)80560-3
• 作为产物：
  描述：

  1-(苯基乙炔基)-1-环己醇 在 甲酸 、 sodium tert-pentoxide 作用下， 以 甲苯 为溶剂， 反应 7.5h， 生成 4-戊烯-1-酮,1-(1-环己烯-1-基)-2-苯基-
  参考文献：
  名称：

  Efficient routes to cyclic 2,3-epoxyalcohols from cycloalkenyl ketones, via cycloalkenyl alcohols

  摘要：

  The minimising of torsional strain and non-bonding interactions is proposed as the explanation of high diastereoselectivity observed in the epoxidation of cycloalkenyl alcohols. reported for twenty three examples. The resulting 2,3-epoxyalcohols are key intermediates in the synthesis of tricyclic 1, 2-diols and beta-hydroxy ketones

  DOI：

  10.1016/s0040-4020(01)80560-3

文献信息

• Regiocontrolled synthesis of furans by a mercury(II) catalysed isomerisation of 1-alkynyl-2,3-epoxyalcohols
  作者：Charles M. Marson、Steven Harper、Roger Wrigglesworth

  DOI：10.1039/c39940001879

  日期：——

  2,3,5-Trisubstituted furans are formed by the reaction of 1-alkynyl-2,3-epoxyalcohols with a catalytic amount of mercury(II) prepared from HgO and dilute sulfuric acid.

  2,3,5-三取代呋喃是通过 1-炔基-2,3-环氧醇与催化量的由 HgO 和稀硫酸制备的汞 (II) 反应形成的。
• Efficient routes to cyclic 2,3-epoxyalcohols from cycloalkenyl ketones, via cycloalkenyl alcohols
  作者：Charles M. Marson、Andrew J. Walker、Jane Pickering、Steven Harper、Roger Wrigglesworth、Simon J. Edge

  DOI：10.1016/s0040-4020(01)80560-3

  日期：1993.1

  The minimising of torsional strain and non-bonding interactions is proposed as the explanation of high diastereoselectivity observed in the epoxidation of cycloalkenyl alcohols. reported for twenty three examples. The resulting 2,3-epoxyalcohols are key intermediates in the synthesis of tricyclic 1, 2-diols and beta-hydroxy ketones