Hydrogen Phthalate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Hydrogen Phthalate
• 英文别名: hydron;phthalate
• 化学式: C₈H₄O₄*2H
• 分子量: 166.133
• InChiKey: XNGIFLGASWRNHJ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  77.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dysprosium(III) nitrate hexahydrate 、 Hydrogen Phthalate 在 1,10-phenanthroline 作用下， 以 水 为溶剂， 以40%的产率得到[Dy2(phthalate)6(H2O)]n
  参考文献：
  名称：

  Slow Relaxation Processes and Single-Ion Magnetic Behaviors in Dysprosium-Containing Complexes

  摘要：

  A series of one-dimensional complexes [Ln(L-1)(3)(HOCH2CH2OH)](n) (L-1 = 2-furoate anion; Ln = Nd (1), Sm (2), Gd (3), Tb (4), Dy (5), Er (6)) have been synthesized. The complexes were crystallized in the monoclinic space group P2(1)/c and show a chain-like structure determined by single-crystal X-ray diffraction. Magnetic properties indicate that carboxyl group of 2-furoate mediates different magnetic couplings in light and heavy rare earth complexes, namely, antiferromagnetic interaction between light rare earth ions and ferromagnetic interaction between heavy ones. Noticeably, complex 5 displays a strong frequency dependence of alternating current (AC) magnetic properties. Further magnetic studies show a distribution of a single relaxation process in 5. While 1,10-phenanthroline and phthalate anion (L-2) were employed, [Dy-2(L-2)(6)(H2O)](n) (7) was isolated by hydrothermal reactions and characterized magnetically. Research results also show the frequency dependence of AC magnetic susceptibilities, although the phthalate anions mediate antiferromagnetic coupling between Dy-III ions. Further magnetic investigation of a neutral mononuclear complex with the formula [Dy(TTA)(3)(L-3)] (8) (TTA = 2-thenoyltrifluoroacetonate; L-3 = 4,5-pinene bipyridine) suggests that the single-ion magnetic behavior originates the slow relaxation of Dy-III-containing complexes.

  DOI：

  10.1021/ic901720a
• 作为产物：
  描述：

  苯酐 在 吡啶 、 碳酸氢钠 、 溶剂黄146 作用下， 以 甲苯 为溶剂， 以70%的产率得到Hydrogen Phthalate
  参考文献：
  名称：

  Dexanabinol derivatives and their use as neuroprotective pharmaceutical

  摘要：

  本发明涉及用于预防或缓解神经毒性的药物组合物。该药物组合物包括作为其活性成分的具有（3S，4S）构型的立体特异性（+）对映体，其为一般式（I）所定义的.DELTA..sup.6-四氢大麻酚（THC）类化合物的对映体。 ##STR1##

  公开号：

  US06096740A1
• 作为试剂：
  描述：

  [2,3:5,6]-di-O-isopropylidene-D-mannose 在 Hydrogen Phthalate 作用下， 生成 O2,O3-isopropylidene-D-mannose
  参考文献：
  名称：

  Freudenberg et al., Chemische Berichte, 1928, vol. 61, p. 1735,1738

  摘要：

  DOI：

文献信息

• Youssef, Abdel-Hamid A.; Sharaf, Saber M.; Hegazy, Fatma M. El, Journal fur praktische Chemie (Leipzig 1954), 1982, vol. 324, # 5, p. 725 - 734
  作者：Youssef, Abdel-Hamid A.、Sharaf, Saber M.、Hegazy, Fatma M. El

  DOI：——

  日期：——
• A biosensor including a catalyst made from phosphate
  申请人：MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD.

  公开号：EP0560336B1

  公开（公告）日：1998-05-06
• Khan, Mohammad Niyaz, journal of the chemical society-perkin transactions 2, 1989, p. 233 - 238
  作者：Khan, Mohammad Niyaz

  DOI：——

  日期：——
• Dexanabinol derivatives and their use as neuroprotective pharmaceutical
  申请人：Ramot University Authority for Applied Research and Industrial

  公开号：US06096740A1

  公开（公告）日：2000-08-01

  The present invention relates to pharmaceutical compositions for preventing or alleviating neurotoxicity. Said pharmaceutical compositions comprise as their active ingredient the stereospecific (+) enantiomers, having (3S,4S) configuration, of .DELTA..sup.6 -tetrahydrocannabinol (THC) type compounds of general formula (I), as defined hereinbelow. ##STR1##

  本发明涉及用于预防或缓解神经毒性的药物组合物。该药物组合物包括作为其活性成分的具有（3S，4S）构型的立体特异性（+）对映体，其为一般式（I）所定义的.DELTA..sup.6-四氢大麻酚（THC）类化合物的对映体。 ##STR1##
• Slow Relaxation Processes and Single-Ion Magnetic Behaviors in Dysprosium-Containing Complexes
  作者：Ying Wang、Xi-Li Li、Tian-Wei Wang、You Song、Xiao-Zeng You

  DOI：10.1021/ic901720a

  日期：2010.2.1

  A series of one-dimensional complexes [Ln(L-1)(3)(HOCH2CH2OH)](n) (L-1 = 2-furoate anion; Ln = Nd (1), Sm (2), Gd (3), Tb (4), Dy (5), Er (6)) have been synthesized. The complexes were crystallized in the monoclinic space group P2(1)/c and show a chain-like structure determined by single-crystal X-ray diffraction. Magnetic properties indicate that carboxyl group of 2-furoate mediates different magnetic couplings in light and heavy rare earth complexes, namely, antiferromagnetic interaction between light rare earth ions and ferromagnetic interaction between heavy ones. Noticeably, complex 5 displays a strong frequency dependence of alternating current (AC) magnetic properties. Further magnetic studies show a distribution of a single relaxation process in 5. While 1,10-phenanthroline and phthalate anion (L-2) were employed, [Dy-2(L-2)(6)(H2O)](n) (7) was isolated by hydrothermal reactions and characterized magnetically. Research results also show the frequency dependence of AC magnetic susceptibilities, although the phthalate anions mediate antiferromagnetic coupling between Dy-III ions. Further magnetic investigation of a neutral mononuclear complex with the formula [Dy(TTA)(3)(L-3)] (8) (TTA = 2-thenoyltrifluoroacetonate; L-3 = 4,5-pinene bipyridine) suggests that the single-ion magnetic behavior originates the slow relaxation of Dy-III-containing complexes.

表征谱图