(Z)-3-methyl-2-((3-methyl-4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)-4,5,6,7-tetrahydro-2H-indole | 1365480-77-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: (Z)-3-methyl-2-((3-methyl-4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)-4,5,6,7-tetrahydro-2H-indole
• CAS: 1365480-77-8
• 化学式: C₁₉H₂₄N₂
• 分子量: 280.413
• InChiKey: VVZXGHYCKAPMMT-ODLFYWEKSA-N

反应信息

• 作为产物：
  描述：

  6,6-difluoro-12,14-dimethyl-2,3,4,6,8,9,10,11-octahydro-1H-[1,3,2]diazaborinino[1,6-a:3,4-a']diindol-5-ium-6-uide 在 水 、 potassium hydroxide 、 叔丁醇 作用下， 反应 0.25h， 以72%的产率得到(Z)-3-methyl-2-((3-methyl-4,5,6,7-tetrahydro-1H-indol-2-yl)methylene)-4,5,6,7-tetrahydro-2H-indole
  参考文献：
  名称：

  Use of F-BODIPYs as a Protection Strategy for Dipyrrins: Optimization of BF₂ Removal

  摘要：

  We recently reported the first general method for the deprotection of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacenes (F-BODIPYs) involving a microwave-assisted procedure for the removal of the BF2 moiety, and liberation of the corresponding free-base dipyrrin. Further optimization of the reaction has resulted in a more convenient and accessible protocol. The availability of this new methodology enables BF2-complexation to be used as a dipyrrin protection strategy. Herein lies a detailed examination of the deprotection reaction, with a view to optimization and gaining mechanistic insight, and its application in facilitating a multistep synthesis of pyrrolyldipyrrins.

  DOI：

  10.1021/jo3002003