n-Butoxy methyl formate | 273223-83-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: n-Butoxy methyl formate
• 英文别名: formic acid butoxymethyl ester；Ameisensaeure-butoxymethylester；Butoxymethyl formate
• CAS: 273223-83-9
• 化学式: C₆H₁₂O₃
• 分子量: 132.159
• InChiKey: MEEGGHGBOIGPMT-UHFFFAOYSA-N

物化性质

• 沸点：
  154 °C
• 密度：
  0.960±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  氯甲基丁基醚 、 sodium formate 生成 n-Butoxy methyl formate
  参考文献：
  名称：

  Walker, vol. 9, p. 187

  摘要：

  DOI：

文献信息

• HALOALKYLSULFONANILIDE DERIVATIVE
  申请人：Kai Masanori

  公开号：US20120029187A1

  公开（公告）日：2012-02-02

  Novel herbicides are provided. A haloalkylsulfonanilide derivative represented by the formula (1) or an agrochemically acceptable salt thereof: the formula (1): wherein Z is —C(R 9 )(R 10 )— or —N(R 11 )—, A is an oxygen atom, a sulfur atom or —N(R 12 )—, W is an oxygen atom or a sulfur atom, m is an integer of from 0 to 3, n is an integer of from 0 to 3, m+n is from 1 to 3, R 1 is halo C 1 -C 6 alkyl, R 2 is a hydrogen atom, C 1 -C 6 alkyl or the like, each of R 3 and R 4 is independently a hydrogen atom, C 1 -C 6 alkyl or the like, each of R 5 , R 6 , R 7 , R 8 , R 9 and R 10 is independently a hydrogen atom, a halogen, C 1 -C 6 alkyl or the like, each of R 11 and R 12 is a hydrogen atom, C 1 -C 6 alkyl, halo C 1 -C 6 alkyl or the like, and X is independently a hydrogen atom, a halogen, C 1 -C 6 alkyl, or the like.

  提供新型除草剂。 一种由式（1）表示的卤烷基磺酰苯胺衍生物或其农药可接受的盐： 式（1）： 其中Z为—C(R9)(R10)—或—N(R11)—，A为氧原子、硫原子或—N(R12)—，W为氧原子或硫原子，m为0至3的整数，n为0至3的整数，m+n为1至3，R1为卤代C1-C6烷基，R2为氢原子、C1-C6烷基或类似物，R3和R4中的每一个独立地为氢原子、C1-C6烷基或类似物，R5、R6、R7、R8、R9和R10中的每一个独立地为氢原子、卤素、C1-C6烷基或类似物，R11和R12中的每一个为氢原子、C1-C6烷基、卤代C1-C6烷基或类似物，X独立地为氢原子、卤素、C1-C6烷基或类似物。
• NOVEL CONDENSED IMIDAZOLE DERIVATIVE
  申请人：Dainippon Sumitomo Pharma Co., Ltd.

  公开号：EP1690863A1

  公开（公告）日：2006-08-16

  Disclosed is a compound represented by the formula (1) below which has a high DPP-IV inhibitory activity and is improved in safety, toxicity and the like. Also disclosed is a prodrug of such a compound and pharmaceutically acceptable salts of them. (In the formula, R1 represents a hydrogen atom, an optionally substituted alkyl group or the like; R2 and R3 independently represent a hydrogen atom, an optionally substituted alkyl group or the like; R4 and R5 independently represent a hydrogen atom, an optionally substituted alkyl group or the like: R6 represents a hydrogen atom, an optionally substituted aryl group or the like; and -Y-NH2, represents a group represented by the following formula (A): (wherein m is 0, 1 or 2; and R7 may not exist or one or two R7 may exist and independently represent an optionally substituted alkyl group or the like) or the like.]

  揭示了一种化合物，其化学式如下（1），具有较高的DPP-IV抑制活性，并在安全性、毒性等方面得到改善。还披露了这种化合物的前药和其药用可接受的盐。（在该式中，R1代表氢原子、可选择取代的烷基或类似物；R2和R3独立代表氢原子、可选择取代的烷基或类似物；R4和R5独立代表氢原子、可选择取代的烷基或类似物；R6代表氢原子、可选择取代的芳基或类似物；-Y-NH2代表由以下式（A）表示的基团：（其中m为0、1或2；R7可能不存在，或一个或两个R7可以存在且独立代表可选择取代的烷基或类似物）或类似物。）
• ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT
  申请人：HOKKO CHEMICAL INDUSTRY CO., LTD.

  公开号：US20200267985A1

  公开（公告）日：2020-08-27

  An isoxazolin-5-one derivative represented by the following (1): wherein R 1 represents a C1-C6 haloalkyl group, and R 2 to R 4 and X each represents a certain substituent or the like; and n represents an integer of 1 to 4, wherein X's may be different from each other when n represents an integer of 2 to 4, and an herbicide containing the isoxazolin-5-one derivative as an active ingredient are provided.

  提供一种由以下式(1)表示的异氧代异噁唑啉-5-酮衍生物：其中R1代表C1-C6卤代烷基，R2到R4和X各代表一定的取代基或类似物；n代表1到4的整数，当n代表2到4的整数时，X可能互不相同，并提供一种以异氧代异噁唑啉-5-酮衍生物为活性成分的除草剂。
• ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS
  申请人：HOKKO CHEMICAL INDUSTRY CO., LTD.

  公开号：US20210309619A1

  公开（公告）日：2021-10-07

  An isoxazolin-5-one derivative represented by formula (1) below: wherein R 1 represents a C1-C6 haloalkyl group, Q represents a C3-C8 cycloalkyl group substituted with a C1-C6 alkoxy group, each of R 2 , R 3 and X represents a certain substituent or the like, and n represents an integer of 1 to 4, wherein X's may be different from each other when n represents an integer of 2 to 4, and a herbicide containing the isoxazolin-5-one derivative as an active ingredient are provided.

  以下是公式（1）所代表的异氧唑啉-5-酮衍生物的中文翻译：其中R1代表一个C1-C6卤代烷基基团，Q代表一个带有一个C1-C6烷氧基团的C3-C8环烷基基团，R2、R3和X中的每一个代表某种取代基或类似物，n代表1到4之间的整数，当n代表2到4之间的整数时，X可能彼此不同，提供了一种含有异氧唑啉-5-酮衍生物作为活性成分的除草剂。
• PHENYLIMIDAZOLE DERIVATIVE, AND THERAPEUTIC MEDICINE OR PREVENTIVE MEDICINE FOR INFLAMMATORY DISEASE, ETC.
  申请人：NIPPON SODA CO., LTD.

  公开号：US20160145242A1

  公开（公告）日：2016-05-26

  A medicinal active ingredient is provided which is useful for the treatment or prevention of inflammatory diseases, diseases caused by lipid oxidation, retinochoroidal disorders. A phenylimidazole derivative represented by Formula (IB) or a salt thereof is provided. A therapeutic medicine or preventive medicine is provided for inflammatory diseases, diseases caused by lipid oxidation, or retinochoroidal disorders, the medicine including at least one selected from the phenylimidazole derivative, a salt thereof, and metabolites thereof as an active ingredient. In Formula (IB), R 1a represents an alkyl group etc., R 2 represents an amino group etc., R 3 represents a halogen atom, an alkyl group etc., R 4 represents a cyano group etc., R 5 represents an alkyl group etc., and R 6 represents an alkyl group etc.

  提供了一种药用活性成分，可用于治疗或预防炎症性疾病、脂质氧化引起的疾病、视网膜脉络膜疾病。提供了一种由式（IB）所代表的苯基咪唑衍生物或其盐，该衍生物可用作治疗或预防炎症性疾病、脂质氧化引起的疾病或视网膜脉络膜疾病的治疗药物或预防药物，该药物包括至少选自苯基咪唑衍生物、其盐和其代谢物中的一种作为活性成分。在式（IB）中，R1代表烷基等，R2代表氨基等，R3代表卤素原子、烷基等，R4代表氰基等，R5代表烷基等，R6代表烷基等。